Detailed information NTG0976680

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: ACM6AU_RS08200
• Genome accession: NZ_CP181097
• Coordinates: 1714804..1716078 (+)
• Length: 424 a.a.
• NCBI ID: WP_001279338.1
• Uniprot ID: A0A0H2XGV4
• Organism: Staphylococcus aureus strain AG21-0627
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1709804..1721078

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AU_RS08180 (ACM6AU_08180)	-	1711137..1711223 (+)	87	WP_153908661.1	hypothetical protein	-
ACM6AU_RS08185 (ACM6AU_08185)	-	1711184..1712314 (-)	1131	WP_000721726.1	HAD family hydrolase	-
ACM6AU_RS08190 (ACM6AU_08190)	nagE	1712421..1713887 (-)	1467	WP_000276359.1	N-acetylglucosamine-specific PTS transporter subunit IIBC	-
ACM6AU_RS08195 (ACM6AU_08195)	-	1714015..1714632 (-)	618	WP_000287588.1	lysophospholipid acyltransferase family protein	-
ACM6AU_RS08200 (ACM6AU_08200)	htrA	1714804..1716078 (+)	1275	WP_001279338.1	S1C family serine protease	Regulator
ACM6AU_RS08205 (ACM6AU_08205)	tyrS	1716172..1717434 (-)	1263	WP_000186034.1	tyrosine--tRNA ligase	-
ACM6AU_RS08210 (ACM6AU_08210)	-	1717815..1718720 (+)	906	WP_000184363.1	transglycosylase domain-containing protein	-
ACM6AU_RS08215 (ACM6AU_08215)	-	1718700..1718786 (-)	87	WP_031785424.1	hypothetical protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 45802.98 Da
• Isoelectric Point: 9.9696

>NTDB_id=976680 ACM6AU_RS08200 WP_001279338.1 1714804..1716078(+) (htrA) [Staphylococcus aureus strain AG21-0627]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide

• Length: 1275 bp

>NTDB_id=976680 ACM6AU_RS08200 WP_001279338.1 1714804..1716078(+) (htrA) [Staphylococcus aureus strain AG21-0627]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATCATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTCCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCCGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTCGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAATCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGTGAACGTACTATTGACGCAGAGACAACTGGAGGTAATACAAAA
GTCAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATTGGGTTTGCCATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATAGACCGCCCTTCAATCGGTATTGGATTAATTAATTTGAAAGATATCCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCAAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAGCCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGCCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (125-269)

• PDZ domain (PDZ_2) (307-397)

3D structure

• AlphaFold DB: A0A0H2XGV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	39.055	94.811	0.37