Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   ACM6AU_RS04425 Genome accession   NZ_CP181097
Coordinates   923437..925245 (+) Length   602 a.a.
NCBI ID   WP_000082725.1    Uniprot ID   A0A2K4AK92
Organism   Staphylococcus aureus strain AG21-0627     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 918437..930245
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6AU_RS04400 (ACM6AU_04400) opp4C 918589..919470 (+) 882 WP_001180265.1 oligopeptide ABC transporter permease -
  ACM6AU_RS04405 (ACM6AU_04405) trpS 919512..920501 (-) 990 WP_000448938.1 tryptophan--tRNA ligase -
  ACM6AU_RS04410 (ACM6AU_04410) spxA 920796..921191 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  ACM6AU_RS04415 (ACM6AU_04415) mecA 921563..922282 (+) 720 WP_001217728.1 adaptor protein MecA -
  ACM6AU_RS04420 (ACM6AU_04420) coiA 922403..923389 (+) 987 WP_000959271.1 competence protein CoiA Machinery gene
  ACM6AU_RS04425 (ACM6AU_04425) pepF 923437..925245 (+) 1809 WP_000082725.1 oligoendopeptidase F Regulator
  ACM6AU_RS04430 (ACM6AU_04430) yjbH 925705..926511 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  ACM6AU_RS04435 (ACM6AU_04435) - 926534..926899 (-) 366 WP_000214067.1 truncated hemoglobin YjbI -
  ACM6AU_RS04440 (ACM6AU_04440) - 927003..927596 (-) 594 WP_000224615.1 CYTH domain-containing protein -
  ACM6AU_RS04445 (ACM6AU_04445) - 927782..928129 (+) 348 WP_001242102.1 hypothetical protein -
  ACM6AU_RS04450 (ACM6AU_04450) - 928146..928781 (+) 636 WP_001077683.1 GTP pyrophosphokinase -
  ACM6AU_RS04455 (ACM6AU_04455) - 928798..929607 (+) 810 WP_001270834.1 NAD kinase -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 69805.37 Da        Isoelectric Point: 4.9226

>NTDB_id=976639 ACM6AU_RS04425 WP_000082725.1 923437..925245(+) (pepF) [Staphylococcus aureus strain AG21-0627]
MSQQLSREEQERKYPEYTWDLTTIFKDDEAFEAAFKEVENELGKEEQFKGHIGDSAETLYNALELEDTLGTKLEKVYVYA
HLKQDQDTTNDKYTGMESRAHQLIIKFSSAWSFLVPEILQIDEDKIQSFVNSYDKLQKFAFDLKLINEKRPHILDAETEK
LLTEAQDALSTPSNVYGMFSNADLVFEDAIDKDGNAHPLTQGTFIKYLESDDRKLRESAFRNVYKAYGAHNNTLGATLAG
EVKKNVFNARTHNYKTAREKALSNNHIPENVYDNLVKTVHKYLPLLHRYTELRKELLGLDDLKMYDLYTPLIKDIKFEMP
YEEAKEWMLKALEPMGEEYLNVVKEGLNNRWVDVYENKGKRSGGYSSGAHLTNPFILLNWSNTISDLYTLVHEFGHSAHS
YFSRKFQPSNSSDYTIFVAEVASTCNEALLSDYMDKHLDDEKRLLLLNQELERFRATLFRQTMFAEFEHKIHAIEEAGEP
LTPTRMNEEYAKLNKLYFGDSVETDEDISKEWSRIPHFYMNYYVYQYATGYSAAQSLSHQILTEGKPAVDRYINEFLKKG
SSNYPIEILKNAGVDMTTPEPIEQACEVFEQKLNAFEKLMKA

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=976639 ACM6AU_RS04425 WP_000082725.1 923437..925245(+) (pepF) [Staphylococcus aureus strain AG21-0627]
ATGAGTCAACAATTATCGAGAGAAGAACAGGAACGTAAATATCCTGAATATACATGGGACTTAACAACAATTTTCAAAGA
TGATGAAGCTTTTGAGGCTGCATTTAAAGAAGTTGAAAATGAGTTAGGCAAAGAAGAACAATTTAAAGGGCACATTGGTG
ATAGTGCTGAGACATTATACAATGCGTTAGAATTAGAAGATACATTAGGTACTAAATTAGAAAAAGTATATGTATACGCG
CATCTAAAACAAGACCAAGATACAACGAACGACAAGTATACTGGTATGGAGTCAAGAGCACATCAATTAATTATTAAATT
TAGCTCGGCATGGAGTTTCTTAGTGCCAGAGATTTTACAAATTGATGAAGATAAAATTCAATCATTTGTAAATTCATATG
ATAAATTACAAAAATTCGCATTTGATTTGAAGTTGATTAATGAAAAACGTCCTCATATTTTAGATGCTGAAACTGAAAAG
TTATTAACAGAAGCGCAGGACGCGTTATCAACACCATCAAATGTATACGGTATGTTTAGCAACGCTGATTTAGTATTTGA
AGATGCGATTGATAAAGATGGAAATGCACATCCGTTAACACAAGGCACATTTATTAAGTATTTAGAATCAGATGATCGCA
AACTAAGAGAAAGTGCTTTTAGAAATGTATATAAAGCATATGGTGCTCATAATAATACGCTTGGCGCTACGCTAGCAGGT
GAAGTGAAGAAAAATGTATTTAATGCTCGTACACACAATTACAAAACTGCAAGAGAAAAAGCATTGAGTAATAATCATAT
TCCAGAAAATGTATATGACAATCTAGTAAAAACTGTACATAAATATTTACCATTGCTACATAGATATACTGAATTGCGCA
AAGAATTGCTAGGTTTAGATGACTTGAAAATGTATGATTTATATACACCATTAATTAAAGATATTAAGTTTGAAATGCCT
TATGAAGAAGCTAAAGAGTGGATGTTAAAAGCTTTAGAACCAATGGGTGAAGAATATTTAAATGTAGTTAAAGAAGGCTT
AAACAATCGTTGGGTCGATGTCTATGAGAATAAAGGTAAACGTTCAGGTGGCTATTCATCAGGTGCACATTTAACTAATC
CATTTATTCTACTTAACTGGTCTAATACTATTTCAGACTTATACACATTAGTTCATGAATTTGGACATTCAGCACATAGT
TACTTCAGTAGAAAATTCCAACCGTCAAATTCTAGTGACTACACTATTTTTGTCGCTGAAGTTGCATCAACTTGTAACGA
AGCACTTTTAAGTGATTATATGGATAAACATCTTGATGATGAAAAACGCTTATTATTATTAAACCAAGAATTAGAACGTT
TCAGAGCTACATTATTCCGACAAACAATGTTCGCAGAATTTGAGCATAAAATTCATGCCATTGAAGAAGCAGGTGAACCA
TTAACGCCAACTAGAATGAATGAAGAATATGCCAAATTAAATAAATTATACTTCGGTGATTCTGTAGAAACTGATGAAGA
TATTAGTAAGGAATGGTCACGTATTCCACACTTCTATATGAATTATTATGTATATCAATACGCAACTGGTTACAGTGCAG
CTCAAAGCTTAAGTCATCAAATTTTAACAGAAGGTAAGCCAGCAGTAGATAGATATATTAATGAATTCTTGAAAAAAGGT
AGCTCAAATTATCCAATTGAGATATTAAAAAATGCTGGTGTAGATATGACAACACCTGAACCAATTGAACAAGCTTGTGA
AGTTTTCGAACAAAAATTGAACGCTTTTGAAAAATTAATGAAAGCTTAG

Domains

Predicted by InterProScan.

Peptidase family M3 (Peptidase_M3)

(207-587)

Oligopeptidase F (Peptidase_M3_N)

(117-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2K4AK92

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

43.952

97.508

0.429