Detailed information NTG0975937

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXQ69_RS13140
• Genome accession: NZ_CP151254
• Coordinates: 2647678..2648565 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain BSN160
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2642678..2653565

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ69_RS13110 (UXQ69_13110)	-	2642694..2642786 (+)	93	WP_010956583.1	hypothetical protein	-
UXQ69_RS13115 (UXQ69_13115)	-	2642894..2643391 (-)	498	WP_001065269.1	glutathione peroxidase	-
UXQ69_RS13120 (UXQ69_13120)	-	2643401..2643661 (-)	261	WP_001789910.1	hypothetical protein	-
UXQ69_RS13125 (UXQ69_13125)	-	2644043..2644156 (-)	114	Protein_2554	hypothetical protein	-
UXQ69_RS13130 (UXQ69_13130)	-	2644817..2646817 (-)	2001	WP_000776739.1	ABC transporter permease	-
UXQ69_RS13135 (UXQ69_13135)	-	2646814..2647569 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXQ69_RS13140 (UXQ69_13140)	braS	2647678..2648565 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXQ69_RS13145 (UXQ69_13145)	braR	2648576..2649241 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXQ69_RS13150 (UXQ69_13150)	-	2649267..2649467 (-)	201	WP_000604727.1	hypothetical protein	-
UXQ69_RS13155 (UXQ69_13155)	-	2649665..2651089 (+)	1425	WP_000953762.1	alkaline phosphatase	-
UXQ69_RS13620	-	2651149..2651250 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXQ69_RS13165 (UXQ69_13165)	-	2651372..2651827 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXQ69_RS13170 (UXQ69_13170)	-	2652072..2652833 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=975937 UXQ69_RS13140 WP_000143420.1 2647678..2648565(-) (braS) [Staphylococcus aureus strain BSN160]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=975937 UXQ69_RS13140 WP_000143420.1 2647678..2648565(-) (braS) [Staphylococcus aureus strain BSN160]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993