Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   UXQ69_RS09960 Genome accession   NZ_CP151254
Coordinates   2020001..2020717 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain BSN160     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2015001..2025717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UXQ69_RS09930 (UXQ69_09930) - 2015217..2015843 (+) 627 WP_000522384.1 nitroreductase family protein -
  UXQ69_RS09935 (UXQ69_09935) - 2016204..2016989 (+) 786 WP_000867942.1 carbon-nitrogen family hydrolase -
  UXQ69_RS13590 hld 2017589..2017669 (-) 81 WP_000046022.1 delta-hemolysin -
  UXQ69_RS09945 (UXQ69_09945) agrB 2017959..2018528 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  UXQ69_RS09950 (UXQ69_09950) agrD 2018525..2018665 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  UXQ69_RS09955 (UXQ69_09955) agrC 2018690..2019982 (+) 1293 WP_341604588.1 quorum-sensing sensor histidine kinase AgrC -
  UXQ69_RS09960 (UXQ69_09960) agrA 2020001..2020717 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  UXQ69_RS09965 (UXQ69_09965) - 2020789..2020898 (+) 110 Protein_1933 hypothetical protein -
  UXQ69_RS09970 (UXQ69_09970) - 2021086..2022045 (-) 960 WP_001253305.1 carbohydrate kinase -
  UXQ69_RS09975 (UXQ69_09975) - 2022042..2023526 (-) 1485 WP_000141430.1 sucrose-6-phosphate hydrolase -
  UXQ69_RS09980 (UXQ69_09980) - 2023675..2024625 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=975933 UXQ69_RS09960 WP_000688492.1 2020001..2020717(+) (agrA) [Staphylococcus aureus strain BSN160]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=975933 UXQ69_RS09960 WP_000688492.1 2020001..2020717(+) (agrA) [Staphylococcus aureus strain BSN160]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGCGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment