Detailed information NTG0975772

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AADP84_RS09980
• Genome accession: NZ_CP151186
• Coordinates: 2033355..2034398 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus argenteus strain Dubai-25
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2028355..2039398

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AADP84_RS09950 (AADP84_09950)	-	2028766..2030013 (-)	1248	WP_000656301.1	aminopeptidase	-
AADP84_RS09955 (AADP84_09955)	-	2030025..2030225 (-)	201	WP_000180459.1	DUF1128 family protein	-
AADP84_RS09960 (AADP84_09960)	-	2030372..2030836 (+)	465	WP_000228669.1	low molecular weight protein-tyrosine-phosphatase	-
AADP84_RS09965 (AADP84_09965)	-	2030843..2031118 (+)	276	WP_000428174.1	YtxH domain-containing protein	-
AADP84_RS09970 (AADP84_09970)	-	2031397..2032620 (+)	1224	WP_000037065.1	YihY/virulence factor BrkB family protein	-
AADP84_RS09975 (AADP84_09975)	vraR	2032736..2033365 (-)	630	WP_000153529.1	two-component system response regulator VraR	Regulator
AADP84_RS09980 (AADP84_09980)	vraS	2033355..2034398 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AADP84_RS09985 (AADP84_09985)	liaF	2034395..2035096 (-)	702	WP_031788217.1	cell wall-active antibiotics response protein LiaF	-
AADP84_RS09990 (AADP84_09990)	-	2035111..2035497 (-)	387	WP_001110170.1	hypothetical protein	-
AADP84_RS09995 (AADP84_09995)	map	2035718..2036476 (-)	759	WP_031788218.1	type I methionyl aminopeptidase	-
AADP84_RS10000 (AADP84_10000)	-	2037007..2037993 (+)	987	WP_031788370.1	aromatic acid exporter family protein	-
AADP84_RS10005 (AADP84_10005)	-	2038625..2039347 (-)	723	WP_031787877.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=975772 AADP84_RS09980 WP_001017131.1 2033355..2034398(-) (vraS) [Staphylococcus argenteus strain Dubai-25]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=975772 AADP84_RS09980 WP_001017131.1 2033355..2034398(-) (vraS) [Staphylococcus argenteus strain Dubai-25]
ATGAACCATTATATTAGAACAATTGGTTCGATGCTCATCTTAGTATACAGCATGCTAGCGGCATTTCTTTTTATAGATAA
AGTTTTCGTTAATATTATTTATTTTCAAGGCATGTTTTATACACAAATATTTGGGATTCCAGTCTTTTTATTTTTAAATC
TCATTATCATTTTATTGTGTATCATCGTCGGATCGGTGCTTGCCTACAAAATTAATCAACAAAATGATTGGATTAAGACA
CAAATTGAGCGTTCTATGGAAGGCGAAACAGTAGGTATCAATGATCAAAATATAGAAATATATAGTGAAACATTAGATTT
ATATCATACGTTAGTACCTTTAAATCAAGAATTGCATAAGTTAAGACTCAAAACGCAAAATTTAACAAATGAAAATTACA
ATATTAATGATGTTAAAGTTAAAAAGATTATCGAAGATGAAAGACAACGTTTAGCTAGAGAACTACACGACTCTGTTAGT
CAACAACTTTTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACGAAATTAGAACCACCTTTAGATCAACAAATACC
TATTTTAGAGAAAATGGTTCAAGATTCTCAGTTAGAAATGCGTGCTTTGCTGCTACACTTAAGACCACTCGGCTTGAAAG
ATAAGTCATTAGGCGAAGGTATTAAAGATTTAGTTATTGATTTACAAAAGAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCAAAAGGTATTGAAGATCATTTATTTAGAATTACGCAAGAAGCAATATCTAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTAGAATTATTTAATAAAGATGATTATTTATTGTTAAGGATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCACTACCAGATTCAGGTACACGTATTGAGGTGAAAGCACCTCTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1