Detailed information NTG0975728

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AADP85_RS09655
• Genome accession: NZ_CP151185
• Coordinates: 1991961..1993004 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus argenteus strain Dubai-30
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1986961..1998004

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AADP85_RS09625 (AADP85_09625)	-	1987372..1988619 (-)	1248	WP_000656301.1	aminopeptidase	-
AADP85_RS09630 (AADP85_09630)	-	1988631..1988831 (-)	201	WP_000180459.1	DUF1128 family protein	-
AADP85_RS09635 (AADP85_09635)	-	1988978..1989442 (+)	465	WP_000228669.1	low molecular weight protein-tyrosine-phosphatase	-
AADP85_RS09640 (AADP85_09640)	-	1989449..1989724 (+)	276	WP_000428174.1	YtxH domain-containing protein	-
AADP85_RS09645 (AADP85_09645)	-	1990003..1991226 (+)	1224	WP_000037065.1	YihY/virulence factor BrkB family protein	-
AADP85_RS09650 (AADP85_09650)	vraR	1991342..1991971 (-)	630	WP_000153529.1	two-component system response regulator VraR	Regulator
AADP85_RS09655 (AADP85_09655)	vraS	1991961..1993004 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AADP85_RS09660 (AADP85_09660)	liaF	1993001..1993702 (-)	702	WP_031788217.1	cell wall-active antibiotics response protein LiaF	-
AADP85_RS09665 (AADP85_09665)	-	1993717..1994103 (-)	387	WP_001110170.1	hypothetical protein	-
AADP85_RS09670 (AADP85_09670)	map	1994324..1995082 (-)	759	WP_031788218.1	type I methionyl aminopeptidase	-
AADP85_RS09675 (AADP85_09675)	-	1995613..1996599 (+)	987	WP_031788370.1	aromatic acid exporter family protein	-
AADP85_RS09680 (AADP85_09680)	-	1997231..1997953 (-)	723	WP_031787877.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=975728 AADP85_RS09655 WP_001017131.1 1991961..1993004(-) (vraS) [Staphylococcus argenteus strain Dubai-30]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=975728 AADP85_RS09655 WP_001017131.1 1991961..1993004(-) (vraS) [Staphylococcus argenteus strain Dubai-30]
ATGAACCATTATATTAGAACAATTGGTTCGATGCTCATCTTAGTATACAGCATGCTAGCGGCATTTCTTTTTATAGATAA
AGTTTTCGTTAATATTATTTATTTTCAAGGCATGTTTTATACACAAATATTTGGGATTCCAGTCTTTTTATTTTTAAATC
TCATTATCATTTTATTGTGTATCATCGTCGGATCGGTGCTTGCCTACAAAATTAATCAACAAAATGATTGGATTAAGACA
CAAATTGAGCGTTCTATGGAAGGCGAAACAGTAGGTATCAATGATCAAAATATAGAAATATATAGTGAAACATTAGATTT
ATATCATACGTTAGTACCTTTAAATCAAGAATTGCATAAGTTAAGACTCAAAACGCAAAATTTAACAAATGAAAATTACA
ATATTAATGATGTTAAAGTTAAAAAGATTATCGAAGATGAAAGACAACGTTTAGCTAGAGAACTACACGACTCTGTTAGT
CAACAACTTTTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACGAAATTAGAACCACCTTTAGATCAACAAATACC
TATTTTAGAGAAAATGGTTCAAGATTCTCAGTTAGAAATGCGTGCTTTGCTGCTACACTTAAGACCACTCGGCTTGAAAG
ATAAGTCATTAGGCGAAGGTATTAAAGATTTAGTTATTGATTTACAAAAGAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCAAAAGGTATTGAAGATCATTTATTTAGAATTACGCAAGAAGCAATATCTAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTAGAATTATTTAATAAAGATGATTATTTATTGTTAAGGATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCACTACCAGATTCAGGTACACGTATTGAGGTGAAAGCACCTCTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1