Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | R8775_RS00405 | Genome accession | NZ_AP026915 |
| Coordinates | 62397..63758 (+) | Length | 453 a.a. |
| NCBI ID | WP_074017595.1 | Uniprot ID | A0A237IXT5 |
| Organism | Streptococcus pneumoniae strain PZ900700005 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 12184..92192 | 62397..63758 | within | 0 |
Gene organization within MGE regions
Location: 12184..92192
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| R8775_RS00065 (PC0005_00130) | ftsH | 12184..14142 (+) | 1959 | WP_000744557.1 | ATP-dependent zinc metalloprotease FtsH | - |
| R8775_RS00070 (PC0005_00140) | comX/comX2 | 14264..14743 (+) | 480 | WP_000588897.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| R8775_RS00105 | - | 20248..21086 (+) | 839 | Protein_14 | IS630 family transposase | - |
| R8775_RS00110 | - | 21121..21918 (-) | 798 | Protein_15 | transposase | - |
| R8775_RS00115 (PC0005_00160) | comW | 22184..22420 (+) | 237 | WP_050233459.1 | sigma(X)-activator ComW | Regulator |
| R8775_RS00120 (PC0005_00170) | - | 22651..23937 (+) | 1287 | WP_000205044.1 | adenylosuccinate synthase | - |
| R8775_RS00125 (PC0005_00180) | - | 24179..25327 (-) | 1149 | WP_000876735.1 | site-specific integrase | - |
| R8775_RS00130 (PC0005_00190) | - | 25499..26413 (-) | 915 | WP_317680939.1 | HIRAN domain-containing protein | - |
| R8775_RS00135 (PC0005_00200) | - | 26426..27160 (-) | 735 | WP_001100508.1 | S24 family peptidase | - |
| R8775_RS00140 (PC0005_00210) | - | 27326..27541 (+) | 216 | WP_000248658.1 | helix-turn-helix domain-containing protein | - |
| R8775_RS00145 (PC0005_00220) | - | 27569..28279 (+) | 711 | WP_024475412.1 | ORF6C domain-containing protein | - |
| R8775_RS00150 (PC0005_00230) | - | 28293..28550 (+) | 258 | WP_000370958.1 | hypothetical protein | - |
| R8775_RS00155 (PC0005_00240) | - | 28636..28956 (+) | 321 | WP_000462824.1 | hypothetical protein | - |
| R8775_RS00160 (PC0005_00250) | - | 28972..29268 (+) | 297 | WP_000391805.1 | hypothetical protein | - |
| R8775_RS00165 (PC0005_00260) | - | 29261..30094 (+) | 834 | WP_024475411.1 | phage replisome organizer N-terminal domain-containing protein | - |
| R8775_RS00170 (PC0005_00270) | - | 30082..30240 (+) | 159 | WP_168952850.1 | hypothetical protein | - |
| R8775_RS00175 (PC0005_00280) | - | 30234..31004 (+) | 771 | WP_050203373.1 | ATP-binding protein | - |
| R8775_RS00180 (PC0005_00290) | - | 31019..31213 (+) | 195 | WP_000470303.1 | hypothetical protein | - |
| R8775_RS00185 (PC0005_00300) | - | 31213..31440 (+) | 228 | WP_000891969.1 | hypothetical protein | - |
| R8775_RS00190 (PC0005_00310) | - | 31567..31731 (+) | 165 | WP_000233201.1 | hypothetical protein | - |
| R8775_RS00195 (PC0005_00320) | - | 31721..31930 (+) | 210 | WP_001105098.1 | hypothetical protein | - |
| R8775_RS00200 (PC0005_00330) | - | 31902..32219 (+) | 318 | WP_000969662.1 | hypothetical protein | - |
| R8775_RS00205 (PC0005_00340) | - | 32221..32730 (+) | 510 | WP_001041150.1 | DUF1642 domain-containing protein | - |
| R8775_RS00210 (PC0005_00350) | - | 32723..33322 (+) | 600 | WP_050201990.1 | DUF1642 domain-containing protein | - |
| R8775_RS00215 (PC0005_00360) | - | 33322..33609 (+) | 288 | WP_000194862.1 | hypothetical protein | - |
| R8775_RS00220 (PC0005_00370) | - | 33609..33797 (+) | 189 | WP_001277861.1 | hypothetical protein | - |
| R8775_RS00225 | - | 33876..33977 (+) | 102 | Protein_38 | DUF3310 domain-containing protein | - |
| R8775_RS00230 (PC0005_00390) | - | 33970..34149 (+) | 180 | WP_000005958.1 | hypothetical protein | - |
| R8775_RS00235 (PC0005_00400) | - | 34136..34369 (+) | 234 | WP_224757171.1 | helix-turn-helix domain-containing protein | - |
| R8775_RS00240 (PC0005_00410) | - | 34441..34869 (+) | 429 | WP_001165368.1 | ArpU family phage packaging/lysis transcriptional regulator | - |
| R8775_RS00245 (PC0005_00420) | - | 35158..35724 (+) | 567 | WP_000754954.1 | site-specific integrase | - |
| R8775_RS00250 (PC0005_00430) | - | 35958..36302 (+) | 345 | WP_001095652.1 | HNH endonuclease | - |
| R8775_RS00255 (PC0005_00440) | - | 36441..37745 (+) | 1305 | WP_000172766.1 | hypothetical protein | - |
| R8775_RS00260 (PC0005_00450) | - | 37699..39090 (+) | 1392 | WP_000228948.1 | hypothetical protein | - |
| R8775_RS00265 (PC0005_00460) | - | 39080..39319 (+) | 240 | WP_000834150.1 | hypothetical protein | - |
| R8775_RS00270 (PC0005_00470) | - | 39372..39602 (+) | 231 | WP_000528517.1 | hypothetical protein | - |
| R8775_RS00275 (PC0005_00480) | - | 39653..41065 (+) | 1413 | WP_000101485.1 | DEAD/DEAH box helicase family protein | - |
| R8775_RS00280 (PC0005_00490) | - | 41147..41611 (+) | 465 | WP_001288685.1 | DUF4355 domain-containing protein | - |
| R8775_RS00285 (PC0005_00500) | - | 41617..42516 (+) | 900 | WP_000774646.1 | phage major capsid protein | - |
| R8775_RS00290 (PC0005_00510) | - | 42522..42734 (+) | 213 | WP_001240369.1 | HeH/LEM domain-containing protein | - |
| R8775_RS00295 (PC0005_00520) | - | 42738..43178 (+) | 441 | WP_000526245.1 | phage Gp19/Gp15/Gp42 family protein | - |
| R8775_RS00300 (PC0005_00530) | - | 43123..43461 (+) | 339 | WP_000221695.1 | hypothetical protein | - |
| R8775_RS00305 (PC0005_00540) | - | 43454..43690 (+) | 237 | WP_000069060.1 | hypothetical protein | - |
| R8775_RS00310 (PC0005_00550) | - | 43687..44022 (+) | 336 | WP_000571659.1 | hypothetical protein | - |
| R8775_RS00315 (PC0005_00560) | - | 44089..44646 (+) | 558 | WP_033683240.1 | hypothetical protein | - |
| R8775_RS00320 (PC0005_00570) | - | 44652..44927 (+) | 276 | WP_000387407.1 | hypothetical protein | - |
| R8775_RS00325 (PC0005_00580) | - | 44939..45325 (+) | 387 | WP_000560881.1 | DUF5361 domain-containing protein | - |
| R8775_RS00330 (PC0005_00590) | - | 45325..47790 (+) | 2466 | WP_000179968.1 | hypothetical protein | - |
| R8775_RS00335 (PC0005_00600) | - | 47790..48488 (+) | 699 | WP_000499607.1 | adenylosuccinate synthetase | - |
| R8775_RS10730 | - | 48485..49402 (+) | 918 | Protein_61 | phage tail spike protein | - |
| R8775_RS00340 (PC0005_00610) | - | 49406..57508 (+) | 8103 | WP_398578204.1 | tail fiber domain-containing protein | - |
| R8775_RS00345 | - | 57505..57621 (+) | 117 | WP_001063632.1 | hypothetical protein | - |
| R8775_RS00350 (PC0005_00620) | - | 57602..57805 (+) | 204 | WP_001091112.1 | hypothetical protein | - |
| R8775_RS00355 (PC0005_00630) | - | 57808..58158 (+) | 351 | WP_000852244.1 | hypothetical protein | - |
| R8775_RS00360 (PC0005_00640) | - | 58168..58584 (+) | 417 | WP_001165339.1 | phage holin family protein | - |
| R8775_RS00365 (PC0005_00650) | - | 58588..58920 (+) | 333 | WP_317680944.1 | phage holin | - |
| R8775_RS00370 (PC0005_00660) | - | 58924..59880 (+) | 957 | WP_000350503.1 | N-acetylmuramoyl-L-alanine amidase family protein | - |
| R8775_RS00375 (PC0005_00670) | - | 60018..60197 (-) | 180 | WP_023937752.1 | hypothetical protein | - |
| R8775_RS00380 (PC0005_00680) | - | 60339..60488 (-) | 150 | WP_001030863.1 | hypothetical protein | - |
| R8775_RS00385 (PC0005_00690) | tadA | 60769..61236 (+) | 468 | WP_000291870.1 | tRNA adenosine(34) deaminase TadA | - |
| R8775_RS00395 (PC0005_00700) | - | 61423..61866 (+) | 444 | WP_000701992.1 | dUTP diphosphatase | - |
| R8775_RS00400 (PC0005_00710) | - | 61868..62383 (+) | 516 | WP_000691236.1 | histidine phosphatase family protein | - |
| R8775_RS00405 (PC0005_00720) | radA | 62397..63758 (+) | 1362 | WP_074017595.1 | DNA repair protein RadA | Machinery gene |
| R8775_RS00410 (PC0005_00730) | - | 63831..64328 (+) | 498 | WP_001809263.1 | carbonic anhydrase | - |
| R8775_RS00415 (PC0005_00740) | - | 64353..65167 (+) | 815 | Protein_76 | PrsW family intramembrane metalloprotease | - |
| R8775_RS00420 (PC0005_00750) | - | 65312..66280 (+) | 969 | WP_000010163.1 | ribose-phosphate diphosphokinase | - |
| R8775_RS00425 | - | 66414..66695 (-) | 282 | Protein_78 | ISL3 family transposase | - |
| R8775_RS00430 | - | 66822..67729 (-) | 908 | Protein_79 | Rpn family recombination-promoting nuclease/putative transposase | - |
| R8775_RS00435 (PC0005_00790) | polA | 67985..70618 (+) | 2634 | WP_050233460.1 | DNA polymerase I | - |
| R8775_RS00440 (PC0005_00800) | - | 70703..71140 (+) | 438 | WP_000076485.1 | CoA-binding protein | - |
| R8775_RS00445 (PC0005_00810) | - | 71323..72333 (-) | 1011 | WP_050244738.1 | YeiH family protein | - |
| R8775_RS00450 (PC0005_00820) | - | 72482..73651 (+) | 1170 | WP_000366345.1 | pyridoxal phosphate-dependent aminotransferase | - |
| R8775_RS00455 (PC0005_00830) | recO | 73648..74418 (+) | 771 | WP_000616162.1 | DNA repair protein RecO | - |
| R8775_RS00460 (PC0005_00840) | plsX | 74415..75407 (+) | 993 | WP_050311686.1 | phosphate acyltransferase PlsX | - |
| R8775_RS00465 (PC0005_00850) | - | 75413..75646 (+) | 234 | WP_000659556.1 | acyl carrier protein | - |
| R8775_RS00470 (PC0005_00860) | - | 75683..75982 (+) | 300 | Protein_87 | transposase family protein | - |
| R8775_RS00475 (PC0005_00870) | blpU | 76184..76414 (+) | 231 | WP_001093075.1 | bacteriocin-like peptide BlpU | - |
| R8775_RS00480 | - | 76417..76542 (+) | 126 | WP_000346297.1 | PncF family bacteriocin immunity protein | - |
| R8775_RS00490 (PC0005_00910) | comA | 78572..80725 (+) | 2154 | WP_050123218.1 | peptide cleavage/export ABC transporter ComA | Regulator |
| R8775_RS00495 (PC0005_00920) | comB | 80738..82087 (+) | 1350 | WP_317680945.1 | competence pheromone export protein ComB | Regulator |
| R8775_RS00500 (PC0005_00930) | purC | 82257..82964 (+) | 708 | WP_050123213.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| R8775_RS00505 | - | 82966..83109 (+) | 144 | WP_317681012.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| R8775_RS00510 (PC0005_00940) | - | 83166..86891 (+) | 3726 | WP_050123211.1 | phosphoribosylformylglycinamidine synthase | - |
| R8775_RS00515 (PC0005_00950) | purF | 86984..88426 (+) | 1443 | WP_000220633.1 | amidophosphoribosyltransferase | - |
| R8775_RS00520 (PC0005_00960) | purM | 88463..89485 (+) | 1023 | WP_001284588.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| R8775_RS00525 (PC0005_00970) | purN | 89482..90027 (+) | 546 | WP_000717505.1 | phosphoribosylglycinamide formyltransferase | - |
| R8775_RS00530 (PC0005_00980) | - | 90111..90620 (+) | 510 | WP_000894018.1 | VanZ family protein | - |
| R8775_RS00535 (PC0005_00990) | purH | 90645..92192 (+) | 1548 | WP_317680946.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49432.95 Da Isoelectric Point: 6.5137
>NTDB_id=97542 R8775_RS00405 WP_074017595.1 62397..63758(+) (radA) [Streptococcus pneumoniae strain PZ900700005]
MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKNARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRV
LGGGVVPGSLVLIGGDPGIGKSTLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAK
RTTTGLDFNRASLIMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGELGLTGEIR
RVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKKVFA
MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKNARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRV
LGGGVVPGSLVLIGGDPGIGKSTLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAK
RTTTGLDFNRASLIMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGELGLTGEIR
RVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKKVFA
Nucleotide
Download Length: 1362 bp
>NTDB_id=97542 R8775_RS00405 WP_074017595.1 62397..63758(+) (radA) [Streptococcus pneumoniae strain PZ900700005]
ATCGCAAAGAAAAAAGCGACATTTGTATGTCAAAATTGTGGGTATAATTCCCCTAAATATCTGGGACGTTGCCCCAACTG
TGGGTCTTGGTCTTCTTTTGTGGAAGAGGTTGAGGTTGCCGAGGTCAAGAATGCGCGTGTGTCCTTGACAGGTGAGAAAA
CCAAGCCCATGAAACTAGCTGAGGTGACTTCCATCAATGTCAATCGAACCAAGACGGAGATGGAGGAATTCAACCGTGTG
CTTGGAGGCGGAGTGGTACCAGGAAGTCTCGTCCTCATTGGTGGGGATCCTGGGATTGGGAAATCAACTCTTCTCCTACA
AGTCTCAACCCAGTTGTCCCAAGTGGGGACAGTTCTCTATGTCAGTGGGGAGGAGTCTGCCCAGCAGATTAAACTACGTG
CAGAGCGCTTAGGTGATATTGATAGTGAGTTTTATCTCTATGCAGAGACCAATATGCAGAGTGTTCGTGCAGAAGTGGAG
CGTATCCAGCCAGACTTTCTCATTATTGATTCCATCCAGACCATCATGTCTCCTGAGATTTCAGGGGTGCAGGGGTCTGT
TTCTCAGGTGCGTGAAGTGACCGCTGAACTCATGCAGTTGGCCAAGACCAATAACATTGCCATCTTTATCGTAGGTCATG
TGACCAAAGAAGGAACCTTGGCTGGGCCTCGTATGTTGGAGCATATGGTGGATACGGTACTTTACTTTGAAGGGGAGCGT
CACCACACCTTTCGTATTTTGAGAGCGGTCAAAAATCGTTTTGGTTCCACTAATGAGATTGGGATTTTTGAGATGCAGTC
GGGCGGCTTGGTTGAGGTACTCAATCCGAGTCAAGTTTTCCTAGAAGAGCGTTTGGATGGGGCGACTGGTTCCTCCATCG
TTGTAACCATGGAAGGGACGCGTCCGATTTTGGCGGAGGTTCAGGCTTTGGTAACACCGACCATGTTTGGAAATGCCAAG
CGTACTACGACAGGACTTGATTTTAACCGTGCTAGCTTGATTATGGCTGTTTTGGAAAAACGGGCAGGGCTTCTCTTGCA
AAATCAGGATGCCTATCTCAAATCTGCTGGTGGTGTTAAATTGGATGAACCTGCGATTGACTTGGCTGTTGCAGTTGCTA
TTGCTTCGAGCTACAAAGACAAGCCAACTAATCCTCAGGAATGTTTTGTCGGAGAACTGGGCTTGACAGGAGAGATTCGG
CGCGTGAATCGTATTGAGCAACGCATCAACGAAGCTGCTAAACTGGGCTTTACTAAGATTTATGTACCTAAGAATTCCTT
GACAGGAATCACTCTGCCTAAGGAAATTCAGGTCATTGGCGTGACAACGATTCAGGAAGTCTTGAAAAAGGTCTTTGCAT
AA
ATCGCAAAGAAAAAAGCGACATTTGTATGTCAAAATTGTGGGTATAATTCCCCTAAATATCTGGGACGTTGCCCCAACTG
TGGGTCTTGGTCTTCTTTTGTGGAAGAGGTTGAGGTTGCCGAGGTCAAGAATGCGCGTGTGTCCTTGACAGGTGAGAAAA
CCAAGCCCATGAAACTAGCTGAGGTGACTTCCATCAATGTCAATCGAACCAAGACGGAGATGGAGGAATTCAACCGTGTG
CTTGGAGGCGGAGTGGTACCAGGAAGTCTCGTCCTCATTGGTGGGGATCCTGGGATTGGGAAATCAACTCTTCTCCTACA
AGTCTCAACCCAGTTGTCCCAAGTGGGGACAGTTCTCTATGTCAGTGGGGAGGAGTCTGCCCAGCAGATTAAACTACGTG
CAGAGCGCTTAGGTGATATTGATAGTGAGTTTTATCTCTATGCAGAGACCAATATGCAGAGTGTTCGTGCAGAAGTGGAG
CGTATCCAGCCAGACTTTCTCATTATTGATTCCATCCAGACCATCATGTCTCCTGAGATTTCAGGGGTGCAGGGGTCTGT
TTCTCAGGTGCGTGAAGTGACCGCTGAACTCATGCAGTTGGCCAAGACCAATAACATTGCCATCTTTATCGTAGGTCATG
TGACCAAAGAAGGAACCTTGGCTGGGCCTCGTATGTTGGAGCATATGGTGGATACGGTACTTTACTTTGAAGGGGAGCGT
CACCACACCTTTCGTATTTTGAGAGCGGTCAAAAATCGTTTTGGTTCCACTAATGAGATTGGGATTTTTGAGATGCAGTC
GGGCGGCTTGGTTGAGGTACTCAATCCGAGTCAAGTTTTCCTAGAAGAGCGTTTGGATGGGGCGACTGGTTCCTCCATCG
TTGTAACCATGGAAGGGACGCGTCCGATTTTGGCGGAGGTTCAGGCTTTGGTAACACCGACCATGTTTGGAAATGCCAAG
CGTACTACGACAGGACTTGATTTTAACCGTGCTAGCTTGATTATGGCTGTTTTGGAAAAACGGGCAGGGCTTCTCTTGCA
AAATCAGGATGCCTATCTCAAATCTGCTGGTGGTGTTAAATTGGATGAACCTGCGATTGACTTGGCTGTTGCAGTTGCTA
TTGCTTCGAGCTACAAAGACAAGCCAACTAATCCTCAGGAATGTTTTGTCGGAGAACTGGGCTTGACAGGAGAGATTCGG
CGCGTGAATCGTATTGAGCAACGCATCAACGAAGCTGCTAAACTGGGCTTTACTAAGATTTATGTACCTAAGAATTCCTT
GACAGGAATCACTCTGCCTAAGGAAATTCAGGTCATTGGCGTGACAACGATTCAGGAAGTCTTGAAAAAGGTCTTTGCAT
AA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus pneumoniae Rx1 |
100 |
100 |
1 |
| radA | Streptococcus pneumoniae D39 |
100 |
100 |
1 |
| radA | Streptococcus pneumoniae R6 |
100 |
100 |
1 |
| radA | Streptococcus pneumoniae TIGR4 |
100 |
100 |
1 |
| radA | Streptococcus mitis NCTC 12261 |
99.558 |
100 |
0.996 |
| radA | Streptococcus mitis SK321 |
99.558 |
100 |
0.996 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
63.135 |
100 |
0.631 |