Detailed information NTG0975416

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR25_RS13885
• Genome accession: NZ_CP151146
• Coordinates: 2755938..2756825 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN152
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2750938..2761825

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR25_RS13855 (UXR25_13860)	-	2750957..2751049 (+)	93	WP_010956583.1	hypothetical protein	-
UXR25_RS13860 (UXR25_13865)	-	2751157..2751654 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXR25_RS13865 (UXR25_13870)	-	2751664..2751924 (-)	261	WP_001791974.1	hypothetical protein	-
UXR25_RS13870 (UXR25_13875)	-	2752306..2752419 (-)	114	Protein_2689	hypothetical protein	-
UXR25_RS13875 (UXR25_13880)	-	2753078..2755078 (-)	2001	WP_000776750.1	ABC transporter permease	-
UXR25_RS13880 (UXR25_13885)	-	2755075..2755830 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXR25_RS13885 (UXR25_13890)	braS	2755938..2756825 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR25_RS13890 (UXR25_13895)	braR	2756836..2757501 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR25_RS13895 (UXR25_13900)	-	2757527..2757727 (-)	201	WP_000604730.1	hypothetical protein	-
UXR25_RS13900 (UXR25_13905)	-	2757925..2759349 (+)	1425	WP_000953755.1	alkaline phosphatase	-
UXR25_RS14980	-	2759409..2759510 (-)	102	WP_000731976.1	SE2200 family small protein	-
UXR25_RS13910 (UXR25_13915)	-	2759632..2760087 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR25_RS13915 (UXR25_13920)	-	2760332..2761093 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=975416 UXR25_RS13885 WP_000143425.1 2755938..2756825(-) (braS) [Staphylococcus aureus strain BSN152]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=975416 UXR25_RS13885 WP_000143425.1 2755938..2756825(-) (braS) [Staphylococcus aureus strain BSN152]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1