Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   UXR25_RS10750 Genome accession   NZ_CP151146
Coordinates   2139437..2140153 (+) Length   238 a.a.
NCBI ID   WP_341514747.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BSN152     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2134437..2145153
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UXR25_RS10720 (UXR25_10720) - 2134654..2135280 (+) 627 WP_000522381.1 nitroreductase family protein -
  UXR25_RS10725 (UXR25_10725) - 2135641..2136426 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  UXR25_RS14955 hld 2137026..2137106 (-) 81 WP_000046022.1 delta-hemolysin -
  UXR25_RS10735 (UXR25_10735) - 2137396..2137959 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  UXR25_RS10740 (UXR25_10740) agrD 2137962..2138105 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  UXR25_RS10745 (UXR25_10745) agrC 2138135..2139418 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  UXR25_RS10750 (UXR25_10750) agrA 2139437..2140153 (+) 717 WP_341514747.1 quorum-sensing response regulator AgrA Regulator
  UXR25_RS10755 (UXR25_10755) - 2140225..2140334 (+) 110 Protein_2079 hypothetical protein -
  UXR25_RS10760 (UXR25_10760) - 2140522..2141481 (-) 960 WP_001253312.1 carbohydrate kinase -
  UXR25_RS10765 (UXR25_10765) - 2141478..2142962 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  UXR25_RS10770 (UXR25_10770) - 2143111..2144061 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27836.79 Da        Isoelectric Point: 5.8598

>NTDB_id=975412 UXR25_RS10750 WP_341514747.1 2139437..2140153(+) (agrA) [Staphylococcus aureus strain BSN152]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNSQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=975412 UXR25_RS10750 WP_341514747.1 2139437..2140153(+) (agrA) [Staphylococcus aureus strain BSN152]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACAGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment