Detailed information NTG0975372

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXQ47_RS13175
• Genome accession: NZ_CP151144
• Coordinates: 2642733..2643620 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain BSN151
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2637733..2648620

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ47_RS13145 (UXQ47_13145)	-	2637751..2637843 (+)	93	WP_010956583.1	hypothetical protein	-
UXQ47_RS13150 (UXQ47_13150)	-	2637951..2638448 (-)	498	WP_001065269.1	glutathione peroxidase	-
UXQ47_RS13155 (UXQ47_13155)	-	2638458..2638718 (-)	261	WP_001789910.1	hypothetical protein	-
UXQ47_RS13160 (UXQ47_13160)	-	2639100..2639213 (-)	114	Protein_2553	hypothetical protein	-
UXQ47_RS13165 (UXQ47_13165)	-	2639872..2641872 (-)	2001	WP_000776739.1	ABC transporter permease	-
UXQ47_RS13170 (UXQ47_13170)	-	2641869..2642624 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXQ47_RS13175 (UXQ47_13175)	braS	2642733..2643620 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXQ47_RS13180 (UXQ47_13180)	braR	2643631..2644296 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXQ47_RS13185 (UXQ47_13185)	-	2644322..2644522 (-)	201	WP_000604727.1	hypothetical protein	-
UXQ47_RS13190 (UXQ47_13190)	-	2644720..2646144 (+)	1425	WP_000953762.1	alkaline phosphatase	-
UXQ47_RS13805	-	2646204..2646305 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXQ47_RS13200 (UXQ47_13200)	-	2646427..2646882 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXQ47_RS13205 (UXQ47_13205)	-	2647127..2647888 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=975372 UXQ47_RS13175 WP_000143420.1 2642733..2643620(-) (braS) [Staphylococcus aureus strain BSN151]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=975372 UXQ47_RS13175 WP_000143420.1 2642733..2643620(-) (braS) [Staphylococcus aureus strain BSN151]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993