Detailed information NTG0975288

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXQ48_RS13070
• Genome accession: NZ_CP151138
• Coordinates: 2645520..2646407 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN164
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2640520..2651407

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ48_RS13040 (UXQ48_13040)	-	2640539..2640631 (+)	93	WP_010956583.1	hypothetical protein	-
UXQ48_RS13045 (UXQ48_13045)	-	2640739..2641236 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXQ48_RS13050 (UXQ48_13050)	-	2641246..2641506 (-)	261	WP_001791974.1	hypothetical protein	-
UXQ48_RS13055 (UXQ48_13055)	-	2641888..2642001 (-)	114	Protein_2530	hypothetical protein	-
UXQ48_RS13060 (UXQ48_13060)	-	2642660..2644660 (-)	2001	WP_000776754.1	ABC transporter permease	-
UXQ48_RS13065 (UXQ48_13065)	-	2644657..2645412 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXQ48_RS13070 (UXQ48_13070)	braS	2645520..2646407 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXQ48_RS13075 (UXQ48_13075)	braR	2646418..2647083 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXQ48_RS13080 (UXQ48_13080)	-	2647109..2647309 (-)	201	WP_000604730.1	hypothetical protein	-
UXQ48_RS13085 (UXQ48_13085)	-	2647507..2648931 (+)	1425	WP_000953755.1	alkaline phosphatase	-
UXQ48_RS13695	-	2648991..2649092 (-)	102	WP_000731976.1	SE2200 family small protein	-
UXQ48_RS13095 (UXQ48_13095)	-	2649214..2649669 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXQ48_RS13100 (UXQ48_13100)	-	2649914..2650675 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=975288 UXQ48_RS13070 WP_000143425.1 2645520..2646407(-) (braS) [Staphylococcus aureus strain BSN164]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=975288 UXQ48_RS13070 WP_000143425.1 2645520..2646407(-) (braS) [Staphylococcus aureus strain BSN164]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1