Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   UXQ48_RS09945 Genome accession   NZ_CP151138
Coordinates   2027470..2028186 (+) Length   238 a.a.
NCBI ID   WP_341532652.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BSN164     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2022470..2033186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UXQ48_RS09915 (UXQ48_09915) - 2022687..2023313 (+) 627 WP_341532651.1 nitroreductase family protein -
  UXQ48_RS09920 (UXQ48_09920) - 2023674..2024459 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  UXQ48_RS13670 hld 2025059..2025139 (-) 81 WP_000046022.1 delta-hemolysin -
  UXQ48_RS09930 (UXQ48_09930) - 2025429..2025992 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  UXQ48_RS09935 (UXQ48_09935) agrD 2025995..2026138 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  UXQ48_RS09940 (UXQ48_09940) agrC 2026168..2027451 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  UXQ48_RS09945 (UXQ48_09945) agrA 2027470..2028186 (+) 717 WP_341532652.1 quorum-sensing response regulator AgrA Regulator
  UXQ48_RS09950 (UXQ48_09950) - 2028258..2028367 (+) 110 Protein_1922 hypothetical protein -
  UXQ48_RS09955 (UXQ48_09955) - 2028555..2029514 (-) 960 WP_001253312.1 carbohydrate kinase -
  UXQ48_RS09960 (UXQ48_09960) - 2029511..2030995 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  UXQ48_RS09965 (UXQ48_09965) - 2031144..2032094 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 28005.04 Da        Isoelectric Point: 6.0927

>NTDB_id=975284 UXQ48_RS09945 WP_341532652.1 2027470..2028186(+) (agrA) [Staphylococcus aureus strain BSN164]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYAWVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=975284 UXQ48_RS09945 WP_341532652.1 2027470..2028186(+) (agrA) [Staphylococcus aureus strain BSN164]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATGGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment