Detailed information NTG0975245

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR56_RS13870
• Genome accession: NZ_CP151129
• Coordinates: 2762047..2762934 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN157
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2757047..2767934

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR56_RS13840 (UXR56_13840)	-	2757066..2757158 (+)	93	WP_010956583.1	hypothetical protein	-
UXR56_RS13845 (UXR56_13845)	-	2757266..2757763 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXR56_RS13850 (UXR56_13850)	-	2757773..2758033 (-)	261	WP_001791974.1	hypothetical protein	-
UXR56_RS13855 (UXR56_13855)	-	2758415..2758528 (-)	114	Protein_2683	hypothetical protein	-
UXR56_RS13860 (UXR56_13860)	-	2759187..2761187 (-)	2001	WP_000776750.1	ABC transporter permease	-
UXR56_RS13865 (UXR56_13865)	-	2761184..2761939 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXR56_RS13870 (UXR56_13870)	braS	2762047..2762934 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR56_RS13875 (UXR56_13875)	braR	2762945..2763610 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR56_RS13880 (UXR56_13880)	-	2763636..2763836 (-)	201	WP_000604730.1	hypothetical protein	-
UXR56_RS13885 (UXR56_13885)	-	2764034..2765458 (+)	1425	WP_000953755.1	alkaline phosphatase	-
UXR56_RS14490	-	2765518..2765619 (-)	102	WP_000731976.1	SE2200 family small protein	-
UXR56_RS13895 (UXR56_13895)	-	2765741..2766196 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR56_RS13900 (UXR56_13900)	-	2766441..2767202 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=975245 UXR56_RS13870 WP_000143425.1 2762047..2762934(-) (braS) [Staphylococcus aureus strain BSN157]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=975245 UXR56_RS13870 WP_000143425.1 2762047..2762934(-) (braS) [Staphylococcus aureus strain BSN157]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1