Detailed information NTG0975240

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXR56_RS10365
• Genome accession: NZ_CP151129
• Coordinates: 2071126..2072169 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN157
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2066126..2077169

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR56_RS10335 (UXR56_10335)	-	2066547..2067803 (-)	1257	WP_001795108.1	aminopeptidase	-
UXR56_RS10340 (UXR56_10340)	-	2067806..2068006 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXR56_RS10345 (UXR56_10345)	-	2068153..2068617 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXR56_RS10350 (UXR56_10350)	-	2068624..2068899 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXR56_RS10355 (UXR56_10355)	-	2069177..2070394 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXR56_RS10360 (UXR56_10360)	vraR	2070507..2071136 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXR56_RS10365 (UXR56_10365)	vraS	2071126..2072169 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXR56_RS10370 (UXR56_10370)	liaF	2072166..2072867 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXR56_RS10375 (UXR56_10375)	-	2072882..2073268 (-)	387	WP_001110179.1	hypothetical protein	-
UXR56_RS10380 (UXR56_10380)	map	2073485..2074243 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXR56_RS10385 (UXR56_10385)	-	2074715..2075701 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
UXR56_RS10390 (UXR56_10390)	-	2076132..2076545 (-)	414	WP_001557448.1	hypothetical protein	-
UXR56_RS10395 (UXR56_10395)	-	2076574..2076684 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=975240 UXR56_RS10365 WP_001017131.1 2071126..2072169(-) (vraS) [Staphylococcus aureus strain BSN157]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=975240 UXR56_RS10365 WP_001017131.1 2071126..2072169(-) (vraS) [Staphylococcus aureus strain BSN157]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1