Detailed information NTG0975154

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ14_RS09460
• Genome accession: NZ_CP151125
• Coordinates: 1941693..1942736 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN154
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1936693..1947736

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ14_RS09430 (UXQ14_09430)	-	1937111..1938367 (-)	1257	WP_001795438.1	aminopeptidase	-
UXQ14_RS09435 (UXQ14_09435)	-	1938370..1938570 (-)	201	WP_000180461.1	DUF1128 family protein	-
UXQ14_RS09440 (UXQ14_09440)	-	1938717..1939181 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ14_RS09445 (UXQ14_09445)	-	1939188..1939463 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ14_RS09450 (UXQ14_09450)	-	1939741..1940958 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ14_RS09455 (UXQ14_09455)	vraR	1941074..1941703 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXQ14_RS09460 (UXQ14_09460)	vraS	1941693..1942736 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ14_RS09465 (UXQ14_09465)	liaF	1942733..1943434 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ14_RS09470 (UXQ14_09470)	-	1943449..1943835 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ14_RS09475 (UXQ14_09475)	map	1944052..1944810 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ14_RS09480 (UXQ14_09480)	-	1945338..1946324 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
UXQ14_RS09485 (UXQ14_09485)	-	1946814..1947227 (-)	414	WP_001549145.1	hypothetical protein	-
UXQ14_RS09490 (UXQ14_09490)	-	1947256..1947366 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=975154 UXQ14_RS09460 WP_001017131.1 1941693..1942736(-) (vraS) [Staphylococcus aureus strain BSN154]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=975154 UXQ14_RS09460 WP_001017131.1 1941693..1942736(-) (vraS) [Staphylococcus aureus strain BSN154]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1