Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R8474_RS09120 Genome accession   NZ_AP026914
Coordinates   1802945..1803769 (-) Length   274 a.a.
NCBI ID   WP_001036775.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700003     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1797945..1808769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8474_RS09115 (PC0003_17930) - 1801323..1802654 (-) 1332 WP_317641883.1 hemolysin family protein -
  R8474_RS09120 (PC0003_17940) endA 1802945..1803769 (-) 825 WP_001036775.1 DNA-entry nuclease EndA Machinery gene
  R8474_RS09125 (PC0003_17950) - 1803808..1803996 (-) 189 WP_001812859.1 DNA-directed RNA polymerase subunit beta -
  R8474_RS09130 (PC0003_17960) murA 1803989..1805272 (-) 1284 WP_000358027.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R8474_RS09135 (PC0003_17970) - 1805296..1805526 (-) 231 WP_000250392.1 DUF1146 family protein -
  R8474_RS09140 (PC0003_17980) sepM 1805584..1806621 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  R8474_RS09145 (PC0003_17990) coaD 1806605..1807093 (-) 489 WP_050221168.1 pantetheine-phosphate adenylyltransferase -
  R8474_RS09150 (PC0003_18000) rsmD 1807083..1807622 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R8474_RS09155 (PC0003_18010) asnA 1807687..1808679 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29976.67 Da        Isoelectric Point: 10.0447

>NTDB_id=97514 R8474_RS09120 WP_001036775.1 1802945..1803769(-) (endA) [Streptococcus pneumoniae strain PZ900700003]
MNKKTRQTLIGLLVLLLLSAGSYYIKQNELGNQAAKTKMSQKKQAPEAPSQELAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=97514 R8474_RS09120 WP_001036775.1 1802945..1803769(-) (endA) [Streptococcus pneumoniae strain PZ900700003]
ATGAACAAAAAAACAAGACAGACACTGATTGGACTGCTAGTGTTATTGCTTTTGTCTGCAGGGAGCTATTATATTAAGCA
GAATGAACTAGGAAATCAGGCTGCTAAGACAAAAATGAGTCAGAAAAAACAAGCGCCTGAAGCTCCTAGTCAAGAATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

95.255

100

0.953
  endA Streptococcus pneumoniae D39

95.255

100

0.953
  endA Streptococcus pneumoniae R6

95.255

100

0.953
  endA Streptococcus pneumoniae TIGR4

95.255

100

0.953

Multiple sequence alignment