Detailed information NTG0975117

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXQ95_RS14310
• Genome accession: NZ_CP151123
• Coordinates: 2816356..2817243 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN46-2
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2811356..2822243

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ95_RS14280 (UXQ95_14280)	-	2811375..2811467 (+)	93	WP_010956583.1	hypothetical protein	-
UXQ95_RS14285 (UXQ95_14285)	-	2811575..2812072 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXQ95_RS14290 (UXQ95_14290)	-	2812082..2812342 (-)	261	WP_001789910.1	hypothetical protein	-
UXQ95_RS14295 (UXQ95_14295)	-	2812724..2812837 (-)	114	WP_001791776.1	hypothetical protein	-
UXQ95_RS14300 (UXQ95_14300)	-	2813496..2815496 (-)	2001	WP_000776751.1	ABC transporter permease	-
UXQ95_RS14305 (UXQ95_14305)	-	2815493..2816248 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXQ95_RS14310 (UXQ95_14310)	braS	2816356..2817243 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXQ95_RS14315 (UXQ95_14315)	braR	2817254..2817919 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXQ95_RS14320 (UXQ95_14320)	-	2817945..2818145 (-)	201	WP_000604728.1	hypothetical protein	-
UXQ95_RS14325 (UXQ95_14325)	-	2818343..2819767 (+)	1425	WP_000953744.1	alkaline phosphatase	-
UXQ95_RS14330 (UXQ95_14330)	-	2819837..2819947 (+)	111	WP_001791296.1	hypothetical protein	-
UXQ95_RS14335 (UXQ95_14335)	-	2820050..2820505 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXQ95_RS14340 (UXQ95_14340)	-	2820750..2821511 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=975117 UXQ95_RS14310 WP_000143419.1 2816356..2817243(-) (braS) [Staphylococcus aureus strain BSN46-2]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=975117 UXQ95_RS14310 WP_000143419.1 2816356..2817243(-) (braS) [Staphylococcus aureus strain BSN46-2]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997