Detailed information NTG0975086

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: ACK2OW_RS20650
• Genome accession: NZ_CP180575
• Coordinates: 3964113..3965195 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain K3C
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3959113..3970195

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACK2OW_RS20635 (ACK2OW_20635)	mcsB	3959121..3960212 (+)	1092	WP_003235007.1	protein arginine kinase	-
ACK2OW_RS20640 (ACK2OW_20640)	clpC	3960209..3962641 (+)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
ACK2OW_RS20645 (ACK2OW_20645)	radA/sms	3962733..3964109 (+)	1377	WP_015252992.1	DNA repair protein RadA	Machinery gene
ACK2OW_RS20650 (ACK2OW_20650)	disA	3964113..3965195 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
ACK2OW_RS20655 (ACK2OW_20655)	yacL	3965311..3966411 (+)	1101	WP_411226393.1	PIN/TRAM domain-containing protein	-
ACK2OW_RS20660 (ACK2OW_20660)	ispD	3966426..3967124 (+)	699	WP_064672086.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
ACK2OW_RS20665 (ACK2OW_20665)	ispF	3967117..3967593 (+)	477	WP_014475594.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
ACK2OW_RS20670 (ACK2OW_20670)	gltX	3967684..3969135 (+)	1452	WP_416042432.1	glutamate--tRNA ligase	-
ACK2OW_RS20675 (ACK2OW_20675)	cysE	3969437..3970090 (+)	654	WP_003225749.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=975086 ACK2OW_RS20650 WP_003225736.1 3964113..3965195(+) (disA) [Bacillus subtilis strain K3C]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=975086 ACK2OW_RS20650 WP_003225736.1 3964113..3965195(+) (disA) [Bacillus subtilis strain K3C]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACCCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1