Detailed information NTG0975069

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ52_RS09990
• Genome accession: NZ_CP151121
• Coordinates: 2012998..2014041 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN55-2
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2007998..2019041

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ52_RS09960 (UXQ52_09960)	-	2008416..2009672 (-)	1257	WP_001795438.1	aminopeptidase	-
UXQ52_RS09965 (UXQ52_09965)	-	2009675..2009875 (-)	201	WP_000180461.1	DUF1128 family protein	-
UXQ52_RS09970 (UXQ52_09970)	-	2010022..2010486 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ52_RS09975 (UXQ52_09975)	-	2010493..2010768 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ52_RS09980 (UXQ52_09980)	-	2011046..2012263 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ52_RS09985 (UXQ52_09985)	vraR	2012379..2013008 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXQ52_RS09990 (UXQ52_09990)	vraS	2012998..2014041 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ52_RS09995 (UXQ52_09995)	liaF	2014038..2014739 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ52_RS10000 (UXQ52_10000)	-	2014754..2015140 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ52_RS10005 (UXQ52_10005)	map	2015357..2016115 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ52_RS10010 (UXQ52_10010)	-	2016587..2017573 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
UXQ52_RS10015 (UXQ52_10015)	-	2018004..2018417 (-)	414	WP_001549145.1	hypothetical protein	-
UXQ52_RS10020 (UXQ52_10020)	-	2018446..2018556 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=975069 UXQ52_RS09990 WP_001017131.1 2012998..2014041(-) (vraS) [Staphylococcus aureus strain BSN55-2]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=975069 UXQ52_RS09990 WP_001017131.1 2012998..2014041(-) (vraS) [Staphylococcus aureus strain BSN55-2]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1