Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   UXQ52_RS00325 Genome accession   NZ_CP151121
Coordinates   70259..71887 (-) Length   542 a.a.
NCBI ID   WP_001631035.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BSN55-2     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 51936..77667 70259..71887 within 0


Gene organization within MGE regions


Location: 51936..77667
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UXQ52_RS00230 (UXQ52_00230) mecA 51936..53945 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  UXQ52_RS00235 (UXQ52_00235) mecR1 54042..55799 (+) 1758 WP_000952923.1 beta-lactam sensor/signal transducer MecR1 -
  UXQ52_RS00240 (UXQ52_00240) mecI 55799..56171 (+) 373 Protein_45 mecA-type methicillin resistance repressor MecI -
  UXQ52_RS00245 (UXQ52_00245) psm-mec 56256..56324 (-) 69 WP_014532405.1 phenol-soluble modulin PSM-mec -
  UXQ52_RS00250 (UXQ52_00250) - 56658..57788 (+) 1131 WP_010922808.1 ROK family transcriptional regulator -
  UXQ52_RS00255 (UXQ52_00255) cstB 57902..59236 (-) 1335 Protein_48 persulfide dioxygenase-sulfurtransferase CstB -
  UXQ52_RS00260 (UXQ52_00260) - 59269..60333 (-) 1065 WP_000438836.1 DsrE/DsrF/DrsH-like family protein -
  UXQ52_RS00265 (UXQ52_00265) cstR 60469..60729 (+) 261 WP_000220507.1 persulfide-sensing transcriptional repressor CstR -
  UXQ52_RS00270 (UXQ52_00270) - 60729..61367 (+) 639 Protein_51 sulfite exporter TauE/SafE family protein -
  UXQ52_RS00275 (UXQ52_00275) - 61712..62374 (-) 663 WP_001092058.1 class I SAM-dependent methyltransferase -
  UXQ52_RS00280 (UXQ52_00280) erm(A) 62883..63614 (+) 732 WP_001072201.1 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) -
  UXQ52_RS00285 (UXQ52_00285) - 63740..64522 (-) 783 WP_000067268.1 aminoglycoside nucleotidyltransferase ANT(9)-Ia -
  UXQ52_RS00290 (UXQ52_00290) - 64673..65050 (-) 378 WP_000361059.1 DUF6262 family protein -
  UXQ52_RS00295 (UXQ52_00295) - 65057..66949 (-) 1893 WP_001557544.1 site-specific integrase -
  UXQ52_RS00300 (UXQ52_00300) - 66946..68031 (-) 1086 WP_000868132.1 tyrosine-type recombinase/integrase -
  UXQ52_RS00305 (UXQ52_00305) - 68150..68467 (-) 318 WP_000659050.1 JAB domain-containing protein -
  UXQ52_RS00310 (UXQ52_00310) - 68488..68994 (-) 507 WP_031836453.1 DUF1643 domain-containing protein -
  UXQ52_RS00315 (UXQ52_00315) - 69010..69321 (-) 312 WP_001631033.1 DUF960 domain-containing protein -
  UXQ52_RS00320 (UXQ52_00320) - 69408..69758 (-) 351 WP_001631034.1 SAUGI family uracil-DNA glycosylase inhibitor -
  UXQ52_RS00325 (UXQ52_00325) ccrB 70259..71887 (-) 1629 WP_001631035.1 recombinase family protein Machinery gene
  UXQ52_RS00330 (UXQ52_00330) ccrA 71884..73245 (-) 1362 WP_001631036.1 recombinase family protein Machinery gene
  UXQ52_RS00335 (UXQ52_00335) - 73432..74061 (-) 630 Protein_64 hypothetical protein -
  UXQ52_RS00340 (UXQ52_00340) - 74070..74408 (+) 339 Protein_65 recombinase family protein -
  UXQ52_RS00345 (UXQ52_00345) - 74520..74879 (-) 360 WP_001631039.1 hypothetical protein -
  UXQ52_RS00350 (UXQ52_00350) - 75086..75412 (+) 327 WP_000391495.1 metalloregulator ArsR/SmtB family transcription factor -
  UXQ52_RS00355 (UXQ52_00355) - 75742..77667 (+) 1926 WP_031783917.1 heavy metal translocating P-type ATPase -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62474.71 Da        Isoelectric Point: 9.6103

>NTDB_id=975037 UXQ52_RS00325 WP_001631035.1 70259..71887(-) (ccrB) [Staphylococcus aureus strain BSN55-2]
MKQLKKKRIGLYARVSTEMQTDGYSIQGQLNQLTEYCQFQGYEVVNEYTDRGISGKTMQRPELQRMLKDANEGKLDCIMV
YKTNRLARNTSDLLNIVEELYKINVEFFSLTEKIEIASSTGKLMLQILASFAEFERNTIVENVYNGQRQRAIEGYYQGNL
PLGYDKVPDSKKELMINQHEANIVKYIFDSYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDRNLWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVLEKYVMDQILEIIKSKKVLKQLVEKVNEKSQIDVSSLNHDIAYKQSQCEE
IKAKMHTLTKTIEDSPDLDSVLKPTILSYQDELNQINNQIYQLEQDKQAEAPHYDADMIANVLQAIFKDIDKLEKSQLKS
LYLTIIDRIDIRKDEHHKKQFYVTLKLNNDIIKQLFNNHPLDEVLPSTSSLFLPQTLYITIE

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=975037 UXQ52_RS00325 WP_001631035.1 70259..71887(-) (ccrB) [Staphylococcus aureus strain BSN55-2]
ATGAAACAACTCAAAAAGAAACGTATTGGATTATATGCACGTGTATCGACTGAAATGCAAACGGATGGTTACAGTATTCA
AGGTCAATTGAATCAACTTACAGAGTATTGTCAATTTCAAGGCTATGAAGTCGTCAATGAATACACCGATCGTGGTATAT
CAGGTAAAACAATGCAACGTCCAGAATTACAACGTATGTTAAAAGATGCCAACGAAGGTAAATTAGATTGTATTATGGTC
TACAAAACAAATCGTTTAGCTAGAAATACCTCAGATTTGTTAAATATTGTCGAGGAATTGTATAAGATTAATGTCGAATT
TTTTAGTCTAACTGAAAAAATAGAAATTGCCAGTTCAACAGGTAAATTGATGCTCCAAATTTTAGCCAGCTTCGCAGAAT
TTGAACGTAATACGATTGTAGAGAATGTCTACAATGGCCAAAGACAACGTGCTATTGAAGGTTATTATCAAGGTAATTTA
CCTCTAGGCTACGATAAAGTACCTGACAGTAAAAAAGAGCTCATGATCAATCAACATGAAGCGAATATTGTTAAATATAT
TTTTGATTCATACGCTAAAGGTCATGGTTATCGTAAGATTGCGAACGCATTGAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCTTTTAGTATTTCGTCCATTACCTACATCATCTCAAACCCTTTTTACATTGGAAAGATACAGTTTGCGAAGTAT
AGACACTGGAGCGATAAAAGACGAAAAGGACTCAATGAGGAACCGATTATCGCTGATGGTAAACATGCGCCTATTATTGA
TAGAAACCTATGGGATAAAGTACAGTTTAAACGTCAAGAGAGTCGCAAGAAACCACAAGTTCACGGCAAAGGAACAAACC
TACTGACTGGGATTGTAAAATGTCCGAAATGTGGTGCAGCAATGGCGGCAAGTAATACAACTAATACATTAAAAGATGGC
ACTAAGAAAAGAATCAGATATTACTCATGTAGCAATTTTAGAAATAAAGGTTCAAAAGTTTGTTCTGCCAATAGCGTTAG
AGCAGATGTACTAGAAAAATATGTTATGGATCAGATATTGGAAATTATCAAAAGCAAAAAGGTATTGAAGCAATTGGTTG
AAAAGGTAAATGAAAAAAGTCAAATAGACGTCTCTTCTTTGAACCATGATATTGCCTATAAACAGTCACAATGTGAAGAA
ATAAAAGCAAAAATGCATACATTAACGAAAACTATTGAAGACTCACCTGACTTAGATAGCGTATTAAAACCAACAATACT
TAGCTACCAAGATGAATTGAATCAAATAAATAATCAAATCTATCAACTAGAACAAGATAAACAAGCAGAAGCTCCACATT
ATGATGCTGATATGATTGCGAATGTACTACAAGCAATATTCAAAGATATAGACAAATTAGAGAAATCTCAGTTGAAATCA
CTATATCTAACAATCATCGATCGCATTGACATAAGAAAAGATGAGCATCATAAGAAGCAATTTTATGTTACGCTCAAGTT
AAATAATGATATAATCAAACAACTATTTAATAACCATCCACTCGACGAAGTGCTCCCTAGCACTTCGTCTTTATTTTTGC
CACAAACTTTATATATAACTATTGAATAA

Domains

Predicted by InterproScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(300-355)

Resolvase, N terminal domain (Resolvase)

(11-154)

Recombinase (Recombinase)

(179-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

72.694

100

0.727

Multiple sequence alignment