Detailed information NTG0975027

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXR13_RS09985
• Genome accession: NZ_CP151118
• Coordinates: 2013007..2014050 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN55
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2008007..2019050

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR13_RS09955 (UXR13_09960)	-	2008425..2009681 (-)	1257	WP_001795438.1	aminopeptidase	-
UXR13_RS09960 (UXR13_09965)	-	2009684..2009884 (-)	201	WP_000180461.1	DUF1128 family protein	-
UXR13_RS09965 (UXR13_09970)	-	2010031..2010495 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXR13_RS09970 (UXR13_09975)	-	2010502..2010777 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXR13_RS09975 (UXR13_09980)	-	2011055..2012272 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXR13_RS09980 (UXR13_09985)	vraR	2012388..2013017 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXR13_RS09985 (UXR13_09990)	vraS	2013007..2014050 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXR13_RS09990 (UXR13_09995)	liaF	2014047..2014748 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXR13_RS09995 (UXR13_10000)	-	2014763..2015149 (-)	387	WP_001110179.1	hypothetical protein	-
UXR13_RS10000 (UXR13_10005)	map	2015366..2016124 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXR13_RS10005 (UXR13_10010)	-	2016596..2017582 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
UXR13_RS10010 (UXR13_10015)	-	2018013..2018426 (-)	414	WP_001549145.1	hypothetical protein	-
UXR13_RS10015 (UXR13_10020)	-	2018455..2018565 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=975027 UXR13_RS09985 WP_001017131.1 2013007..2014050(-) (vraS) [Staphylococcus aureus strain BSN55]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=975027 UXR13_RS09985 WP_001017131.1 2013007..2014050(-) (vraS) [Staphylococcus aureus strain BSN55]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1