Detailed information NTG0974941

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ49_RS09475
• Genome accession: NZ_CP151113
• Coordinates: 1922991..1924034 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN165
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1917991..1929034

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ49_RS09445 (UXQ49_09445)	-	1918412..1919659 (-)	1248	WP_000656302.1	aminopeptidase	-
UXQ49_RS09450 (UXQ49_09450)	-	1919671..1919871 (-)	201	WP_000180459.1	DUF1128 family protein	-
UXQ49_RS09455 (UXQ49_09455)	-	1920018..1920482 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ49_RS09460 (UXQ49_09460)	-	1920489..1920764 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ49_RS09465 (UXQ49_09465)	-	1921042..1922259 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
UXQ49_RS09470 (UXQ49_09470)	vraR	1922372..1923001 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXQ49_RS09475 (UXQ49_09475)	vraS	1922991..1924034 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ49_RS09480 (UXQ49_09480)	liaF	1924031..1924732 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ49_RS09485 (UXQ49_09485)	-	1924747..1925133 (-)	387	WP_049296041.1	hypothetical protein	-
UXQ49_RS09490 (UXQ49_09490)	map	1925350..1926108 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
UXQ49_RS09495 (UXQ49_09495)	-	1926639..1927625 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
UXQ49_RS09500 (UXQ49_09500)	-	1927803..1928216 (-)	414	WP_001622129.1	hypothetical protein	-
UXQ49_RS09505 (UXQ49_09505)	-	1928245..1928354 (-)	110	Protein_1838	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=974941 UXQ49_RS09475 WP_001017131.1 1922991..1924034(-) (vraS) [Staphylococcus aureus strain BSN165]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=974941 UXQ49_RS09475 WP_001017131.1 1922991..1924034(-) (vraS) [Staphylococcus aureus strain BSN165]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1