Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   R8474_RS04450 Genome accession   NZ_AP026914
Coordinates   866031..866840 (+) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain PZ900700003     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 861031..871840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8474_RS04430 - 862531..862656 (-) 126 WP_001818232.1 hypothetical protein -
  R8474_RS04435 (PC0003_08790) mutY 862753..863928 (+) 1176 WP_000886147.1 A/G-specific adenine glycosylase -
  R8474_RS04440 (PC0003_08800) micA 863983..864687 (+) 705 WP_000722076.1 response regulator YycF Regulator
  R8474_RS04445 (PC0003_08810) micB 864680..866029 (+) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  R8474_RS04450 (PC0003_08820) vicX 866031..866840 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  R8474_RS04455 (PC0003_08830) relB 866931..867173 (+) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  R8474_RS04460 (PC0003_08840) - 867175..867429 (+) 255 WP_001812387.1 type II toxin-antitoxin system RelE/ParE family toxin -
  R8474_RS04465 (PC0003_08850) - 867476..868249 (+) 774 WP_000731132.1 ion transporter -
  R8474_RS04470 (PC0003_08860) - 868512..869498 (-) 987 WP_000204727.1 L-lactate dehydrogenase -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=97484 R8474_RS04450 WP_001289493.1 866031..866840(+) (vicX) [Streptococcus pneumoniae strain PZ900700003]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=97484 R8474_RS04450 WP_001289493.1 866031..866840(+) (vicX) [Streptococcus pneumoniae strain PZ900700003]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTGGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGCAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACTTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGACAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCAGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment