Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ACMX77_RS09230 Genome accession   NZ_CP180438
Coordinates   1770846..1772729 (+) Length   627 a.a.
NCBI ID   WP_015483240.1    Uniprot ID   -
Organism   Bacillus subtilis strain W-2     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1765846..1777729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACMX77_RS09215 (ACMX77_09215) ymcA 1766883..1767314 (+) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator
  ACMX77_RS09220 (ACMX77_09220) cotE 1767576..1768121 (+) 546 WP_003231833.1 outer spore coat protein CotE -
  ACMX77_RS09225 (ACMX77_09225) hexA 1768254..1770830 (+) 2577 WP_015483239.1 DNA mismatch repair protein MutS Machinery gene
  ACMX77_RS09230 (ACMX77_09230) hexB 1770846..1772729 (+) 1884 WP_015483240.1 DNA mismatch repair endonuclease MutL Machinery gene
  ACMX77_RS09235 (ACMX77_09235) ymzD 1773129..1773584 (-) 456 WP_015483241.1 regulatory YrvL family protein -
  ACMX77_RS09240 (ACMX77_09240) - 1773740..1774297 (-) 558 WP_047182628.1 hypothetical protein -
  ACMX77_RS09245 (ACMX77_09245) pksA 1774418..1775035 (+) 618 WP_015383700.1 TetR/AcrR family transcriptional regulator -
  ACMX77_RS09250 (ACMX77_09250) pksB 1775225..1775902 (+) 678 WP_003231824.1 MBL fold metallo-hydrolase -
  ACMX77_RS09255 (ACMX77_09255) - 1776012..1776278 (+) 267 WP_120363368.1 hypothetical protein -
  ACMX77_RS09260 (ACMX77_09260) fabD 1776275..1777141 (+) 867 WP_047182629.1 ACP S-malonyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70484.35 Da        Isoelectric Point: 5.6008

>NTDB_id=974712 ACMX77_RS09230 WP_015483240.1 1770846..1772729(+) (hexB) [Bacillus subtilis strain W-2]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQLPKKSAPVIKNEQQFITFDEKPAEKKVPEKSTASSYSPMKLSSVVKEPLDAEEELPPLQFDAPPI
VDQEQTLEVSDVSAEEPETFEQECHEEQQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQDMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=974712 ACMX77_RS09230 WP_015483240.1 1770846..1772729(+) (hexB) [Bacillus subtilis strain W-2]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGATGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGACTTGCAT
CCATTCGGGTTTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGTGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACAGATGTGGTGAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTCCCGCTGCATGTGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAACGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATACGTGACGGA
ATTAAAGATGTGTTTAAACAGCAGCAGCTGATTCCGAGTGCCCAGCTCCCGAAAAAATCGGCACCTGTAATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTGCGGAAAAAAAAGTTCCGGAAAAATCGACTGCGTCATCTTATTCACCAA
TGAAGCTCAGTTCAGTCGTAAAAGAGCCGCTTGATGCGGAGGAAGAATTGCCTCCTCTCCAATTTGATGCTCCTCCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATGTTTCAGCAGAAGAGCCTGAAACATTTGAGCAGGAATGCCATGAGGA
ACAGCAGCAGCCAGCGTCTGAGCGGGTTCCGATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTGTATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTCCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTGCAGGATATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTGGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCGG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTCATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGACGA
AATCAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATACACC
ATTCCACTTATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(442-583)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.652

100

0.469