Detailed information NTG0973578

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ99_RS09505
• Genome accession: NZ_CP150893
• Coordinates: 1940497..1941540 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN182
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1935497..1946540

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ99_RS09475 (UXQ99_09475)	-	1935918..1937174 (-)	1257	WP_001795108.1	aminopeptidase	-
UXQ99_RS09480 (UXQ99_09480)	-	1937177..1937377 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXQ99_RS09485 (UXQ99_09485)	-	1937524..1937988 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ99_RS09490 (UXQ99_09490)	-	1937995..1938270 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ99_RS09495 (UXQ99_09495)	-	1938548..1939765 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ99_RS09500 (UXQ99_09500)	vraR	1939878..1940507 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXQ99_RS09505 (UXQ99_09505)	vraS	1940497..1941540 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ99_RS09510 (UXQ99_09510)	liaF	1941537..1942238 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ99_RS09515 (UXQ99_09515)	-	1942253..1942639 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ99_RS09520 (UXQ99_09520)	map	1942856..1943614 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ99_RS09525 (UXQ99_09525)	-	1944145..1945131 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
UXQ99_RS09530 (UXQ99_09530)	-	1945562..1945975 (-)	414	WP_001557448.1	hypothetical protein	-
UXQ99_RS09535 (UXQ99_09535)	-	1946004..1946114 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=973578 UXQ99_RS09505 WP_001017131.1 1940497..1941540(-) (vraS) [Staphylococcus aureus strain BSN182]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=973578 UXQ99_RS09505 WP_001017131.1 1940497..1941540(-) (vraS) [Staphylococcus aureus strain BSN182]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1