Detailed information NTG0973504

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXR26_RS09825
• Genome accession: NZ_CP150888
• Coordinates: 2000236..2001279 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN181
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1995236..2006279

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR26_RS09795 (UXR26_09795)	-	1995657..1996913 (-)	1257	WP_001795108.1	aminopeptidase	-
UXR26_RS09800 (UXR26_09800)	-	1996916..1997116 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXR26_RS09805 (UXR26_09805)	-	1997263..1997727 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXR26_RS09810 (UXR26_09810)	-	1997734..1998009 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXR26_RS09815 (UXR26_09815)	-	1998287..1999504 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXR26_RS09820 (UXR26_09820)	vraR	1999617..2000246 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXR26_RS09825 (UXR26_09825)	vraS	2000236..2001279 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXR26_RS09830 (UXR26_09830)	liaF	2001276..2001977 (-)	702	WP_000149065.1	cell wall-active antibiotics response protein LiaF	-
UXR26_RS09835 (UXR26_09835)	-	2001992..2002378 (-)	387	WP_001110179.1	hypothetical protein	-
UXR26_RS09840 (UXR26_09840)	map	2002595..2003353 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXR26_RS09845 (UXR26_09845)	-	2003884..2004870 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
UXR26_RS09850 (UXR26_09850)	-	2005301..2005714 (-)	414	WP_001557448.1	hypothetical protein	-
UXR26_RS09855 (UXR26_09855)	-	2005743..2005853 (-)	111	WP_057488483.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=973504 UXR26_RS09825 WP_001017131.1 2000236..2001279(-) (vraS) [Staphylococcus aureus strain BSN181]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=973504 UXR26_RS09825 WP_001017131.1 2000236..2001279(-) (vraS) [Staphylococcus aureus strain BSN181]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1