Detailed information NTG0973305

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ34_RS09695
• Genome accession: NZ_CP150881
• Coordinates: 1958229..1959272 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN180
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1953229..1964272

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ34_RS09665 (UXQ34_09665)	-	1953647..1954903 (-)	1257	WP_001795438.1	aminopeptidase	-
UXQ34_RS09670 (UXQ34_09670)	-	1954906..1955106 (-)	201	WP_000180461.1	DUF1128 family protein	-
UXQ34_RS09675 (UXQ34_09675)	-	1955253..1955717 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ34_RS09680 (UXQ34_09680)	-	1955724..1955999 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ34_RS09685 (UXQ34_09685)	-	1956277..1957494 (+)	1218	WP_000037069.1	YihY/virulence factor BrkB family protein	-
UXQ34_RS09690 (UXQ34_09690)	vraR	1957610..1958239 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXQ34_RS09695 (UXQ34_09695)	vraS	1958229..1959272 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ34_RS09700 (UXQ34_09700)	liaF	1959269..1959970 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ34_RS09705 (UXQ34_09705)	-	1959985..1960371 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ34_RS09710 (UXQ34_09710)	map	1960588..1961346 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ34_RS09715 (UXQ34_09715)	-	1961933..1962919 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
UXQ34_RS09720 (UXQ34_09720)	-	1963350..1963763 (-)	414	WP_001549145.1	hypothetical protein	-
UXQ34_RS09725 (UXQ34_09725)	-	1963792..1963902 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=973305 UXQ34_RS09695 WP_001017131.1 1958229..1959272(-) (vraS) [Staphylococcus aureus strain BSN180]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=973305 UXQ34_RS09695 WP_001017131.1 1958229..1959272(-) (vraS) [Staphylococcus aureus strain BSN180]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1