Detailed information NTG0973257

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: WMY90_RS08985
• Genome accession: NZ_CP150875
• Coordinates: 1728915..1729814 (+)
• Length: 299 a.a.
• NCBI ID: WP_002946143.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TCI125
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 1723915..1734814

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WMY90_RS08965 (WMY90_08965)	trkA	1725051..1726400 (-)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-
WMY90_RS08970 (WMY90_08970)	-	1726689..1727198 (+)	510	WP_022096566.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
WMY90_RS08975 (WMY90_08975)	-	1727510..1728067 (+)	558	WP_002946140.1	ECF transporter S component	-
WMY90_RS08980 (WMY90_08980)	-	1728070..1728720 (+)	651	WP_022096567.1	phosphatase PAP2 family protein	-
WMY90_RS08985 (WMY90_08985)	comR	1728915..1729814 (+)	900	WP_002946143.1	helix-turn-helix domain-containing protein	Regulator
WMY90_RS08990 (WMY90_08990)	-	1730052..1731230 (+)	1179	Protein_1721	ABC transporter transmembrane domain-containing protein	-
WMY90_RS08995 (WMY90_08995)	comA	1731252..1731461 (+)	210	WP_002946147.1	hypothetical protein	Regulator
WMY90_RS09000 (WMY90_09000)	-	1731516..1732084 (+)	569	Protein_1723	ATP-binding cassette domain-containing protein	-
WMY90_RS09005 (WMY90_09005)	-	1732192..1732503 (+)	312	WP_022096570.1	DUF805 domain-containing protein	-
WMY90_RS09010 (WMY90_09010)	-	1732471..1732755 (-)	285	WP_232085805.1	hypothetical protein	-
WMY90_RS09015 (WMY90_09015)	-	1732995..1733891 (-)	897	WP_224103642.1	urease cluster protein	-
WMY90_RS09020 (WMY90_09020)	-	1734296..1734811 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35303.77 Da
• Isoelectric Point: 5.1073

>NTDB_id=973257 WMY90_RS08985 WP_002946143.1 1728915..1729814(+) (comR) [Streptococcus thermophilus strain TCI125]
MNLKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=973257 WMY90_RS08985 WP_002946143.1 1728915..1729814(+) (comR) [Streptococcus thermophilus strain TCI125]
TTGAACTTAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	99.666	100	0.997
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418