Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   WMY90_RS01165 Genome accession   NZ_CP150875
Coordinates   219526..221784 (-) Length   752 a.a.
NCBI ID   WP_022096966.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TCI125     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 214526..226784
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WMY90_RS01135 (WMY90_01135) - 214924..215544 (+) 621 WP_002947316.1 DUF3862 domain-containing protein -
  WMY90_RS01140 (WMY90_01140) - 215756..216298 (+) 543 WP_002947314.1 VTT domain-containing protein -
  WMY90_RS01145 (WMY90_01145) - 216276..217511 (+) 1236 WP_002947307.1 aminoacyltransferase -
  WMY90_RS01150 (WMY90_01150) - 217610..218572 (+) 963 Protein_215 Gfo/Idh/MocA family oxidoreductase -
  WMY90_RS01155 (WMY90_01155) - 218613..218915 (-) 303 WP_002947303.1 DUF1827 family protein -
  WMY90_RS01160 (WMY90_01160) - 218925..219383 (-) 459 WP_002947302.1 NUDIX hydrolase -
  WMY90_RS01165 (WMY90_01165) clpE 219526..221784 (-) 2259 WP_022096966.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  WMY90_RS01170 (WMY90_01170) argF 222025..223005 (+) 981 WP_022096967.1 ornithine carbamoyltransferase -
  WMY90_RS01175 (WMY90_01175) - 223074..223304 (+) 231 WP_011225686.1 DUF1797 family protein -
  WMY90_RS01180 (WMY90_01180) - 223573..224253 (+) 681 WP_014608117.1 amino acid ABC transporter permease -
  WMY90_RS01185 (WMY90_01185) - 224253..224987 (+) 735 WP_011225688.1 amino acid ABC transporter ATP-binding protein -
  WMY90_RS01190 (WMY90_01190) - 225161..225637 (+) 477 WP_011225689.1 ferrous iron transport protein A -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83756.97 Da        Isoelectric Point: 5.2761

>NTDB_id=973209 WMY90_RS01165 WP_022096966.1 219526..221784(-) (clpE) [Streptococcus thermophilus strain TCI125]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQHCYKIIKSDPENPLNQFNQAGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGPGRPGGPRQQAPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVGKT
AVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNTGDGNM
DAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAITAAA
ELSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFIDPKDLDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMKQQTI
KDQDMPIITEKHIEAIVEQKTNIPIGDLKEKEQSQLLNLADDLKAHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIGSFLF
VGPTGVGKTELSKQLAIELFGSSDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEKAH
PDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSVINHLGDFFSPEFMNRFDGIIE
FSALSKENLLTIVDLMLDGVNQRLANNGIHLSVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLKNPNEKDL
KAVMTSKGHITIKSAKKTEKTSQKTEALKEVN

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=973209 WMY90_RS01165 WP_022096966.1 219526..221784(-) (clpE) [Streptococcus thermophilus strain TCI125]
ATGCTCTGCCAAAACTGTAACCTTAATGAAGCTAGTATCCATTTGTATACCAACGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAACATTGTTATAAAATCATAAAATCTGATCCAGAGAACCCCCTTAACCAATTCAATCAAGCAGGAGGTTCCA
ACTTCTTCGACGATTTCTTCAGTGACCTAAACAACTTCCGTTCTTCTAACGGAGACCTTCCTAATACACCTCCAACACAA
GAGGGAGGTAACCGTGGAAACGGTGGTCCAGGCCGTCCTGGAGGACCACGTCAACAAGCCCCTCAACAACCTCAAGGCCT
TCTCGAAGAATTTGGAATTAATATCACAGATATTGCTCGTCGTGGAGACATTGATCCTGTCATTGGTCGTGACGAAGAAA
TCATTCGCGTCATCGAAATTCTGAACCGCCGTACCAAGAACAATCCTGTTCTTATCGGTGAACCTGGTGTTGGTAAGACC
GCAGTAGTCGAAGGACTTGCCCAAAAAATCGTTGATGGAGATGTGCCACAAAAACTCCAAAGCAAGCAAGTTATCCGTCT
TGATGTTGTAAGCCTAGTTCAAGGGACTGGTATCCGCGGCCAGTTCGAAGAACGCATGCAAAAGCTCATGGAGGAAATCC
GCCAACGTCAGGATGTTATCCTCTTTATTGATGAAATCCATGAAATTGTAGGAGCTGGTAATACTGGGGACGGCAATATG
GATGCTGGAAACATCTTAAAACCTGCACTTGCCCGTGGAGAGCTTCAACTTGTTGGAGCAACAACACTCAACGAATACCG
TATCATTGAGAAAGATGCGGCACTCGAACGTCGTATGCAACCTGTTAAGGTAGATGAGCCAACAGTTGAGGAAACAATCA
CAATTTTGCGTGGTATCCAGCCTAAATATCAAGACTACCACCATGTCAAATACACTGATGAAGCCATTACTGCAGCTGCA
GAATTATCCAACCGCTACATTCAGGACCGTTTCTTGCCAGATAAGGCCATCGACCTTCTCGATGAATCTGGCTCTAAGAT
GAATTTAACCCTCAACTTTATCGATCCTAAGGACCTCGATAAACGTTTGATTGAAGCTGAGAATCTTAAAGCTCAGGCTA
CTCGTGACGAAGACTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCTAAATACAAGGAAATGAAACAGCAAACCATC
AAAGACCAAGATATGCCTATCATTACTGAAAAACATATCGAAGCCATTGTCGAGCAAAAAACCAATATTCCTATCGGTGA
TTTAAAAGAAAAAGAACAATCTCAACTTCTCAACCTCGCCGATGACCTTAAGGCGCATGTTATTGGCCAAGATGCCGCAG
TTGATAAGATTGCCAAAGCTATCCGCCGTAATCGTGTTGGACTTGGTGCACCAAACCGCCCAATTGGTAGCTTCCTATTT
GTAGGCCCTACAGGAGTCGGTAAAACTGAGCTCTCTAAACAGTTAGCCATCGAGCTCTTTGGTTCATCTGATAGTATGAT
TCGTTTTGACATGTCAGAATACATGGAAAAACACGCTGTTGCTAAATTGGTCGGTGCTCCTCCAGGCTATGTTGGTTACG
ACGAAGCTGGGCAATTAACCGAAAAGGTCCGCCGTAACCCTTATTCACTCATTCTCCTTGATGAGGTTGAAAAAGCTCAC
CCAGATGTGCTTCACATGTTCCTTCAGGTACTTGACGATGGTCGTCTGACTGATGGTCAAGGGAGAACTGTAAGTTTCAA
AGATACCATCATCATCATGACTTCAAATGCTGGTACTGGTAAAGTGGAAGCAAGTGTAGGTTTTGGAGCTGCTCGTGAGA
ATCGTACCAATTCTGTTATCAACCACCTCGGAGATTTCTTCAGTCCTGAATTCATGAACCGTTTTGACGGTATTATCGAG
TTCTCTGCCCTAAGCAAGGAAAATCTCCTTACTATCGTGGATCTTATGCTTGATGGCGTCAACCAACGCTTGGCAAACAA
CGGTATCCACCTCAGTGTGACTGATAAAGTTAAGGAAAAACTGGTTGACCTTGGTTATGATCCTAAGATGGGTGCTCGAC
CATTGCGTCGTACAATCCAAGACCACATCGAAGATGCCATTACAGACTTCTACCTTAAAAATCCAAATGAAAAAGATCTC
AAGGCTGTAATGACTTCAAAGGGACACATCACCATTAAATCTGCTAAAAAAACTGAAAAAACTTCTCAGAAAACTGAAGC
ATTAAAAGAAGTCAACTAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(288-386)

AAA domain (Cdc48 subfamily) (AAA_2)

(473-636)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(644-717)

ATPase family associated with various cellular activities (AAA) (AAA)

(150-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

84.421

99.867

0.843
  clpE Streptococcus pneumoniae Rx1

82.048

100

0.82
  clpE Streptococcus pneumoniae D39

82.048

100

0.82
  clpE Streptococcus pneumoniae R6

82.048

100

0.82
  clpE Streptococcus pneumoniae TIGR4

81.915

100

0.819
  clpC Lactococcus lactis subsp. cremoris KW2

76.368

99.601

0.761
  clpC Bacillus subtilis subsp. subtilis str. 168

51.772

86.303

0.447
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.657

87.5

0.408
  clpC Streptococcus pneumoniae Rx1

46.984

83.777

0.394
  clpC Streptococcus pneumoniae D39

46.984

83.777

0.394
  clpC Streptococcus pneumoniae TIGR4

46.825

83.777

0.392
  clpC Streptococcus mutans UA159

46.486

83.245

0.387
  clpC Streptococcus thermophilus LMD-9

46.4

83.112

0.386
  clpC Streptococcus thermophilus LMG 18311

46.314

82.979

0.384

Multiple sequence alignment