Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   AAAF57_RS08620 Genome accession   NZ_CP150847
Coordinates   1876606..1878135 (-) Length   509 a.a.
NCBI ID   WP_014633896.1    Uniprot ID   A0AB33ZGE8
Organism   Streptococcus salivarius strain KSS5     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1871606..1883135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAAF57_RS08595 (AAAF57_08635) - 1871818..1872447 (-) 630 WP_410536536.1 HI_0552 family protein -
  AAAF57_RS08600 (AAAF57_08640) der 1872512..1873822 (-) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  AAAF57_RS08605 (AAAF57_08645) dnaI 1873927..1874829 (-) 903 WP_014633898.1 primosomal protein DnaI -
  AAAF57_RS08610 (AAAF57_08650) - 1874833..1876008 (-) 1176 WP_037610617.1 DnaD domain protein -
  AAAF57_RS08615 (AAAF57_08655) nrdR 1876005..1876484 (-) 480 WP_002883820.1 transcriptional regulator NrdR -
  AAAF57_RS08620 (AAAF57_08660) covS 1876606..1878135 (-) 1530 WP_014633896.1 HAMP domain-containing histidine kinase Regulator
  AAAF57_RS08625 (AAAF57_08665) covR 1878132..1878821 (-) 690 WP_002883757.1 response regulator transcription factor Regulator
  AAAF57_RS08630 (AAAF57_08670) - 1878977..1879513 (-) 537 WP_037600313.1 DUF177 domain-containing protein -
  AAAF57_RS08635 (AAAF57_08675) rsmG 1879812..1880525 (+) 714 WP_037600311.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  AAAF57_RS08640 (AAAF57_08680) - 1880594..1881958 (+) 1365 WP_410536539.1 TrkH family potassium uptake protein -
  AAAF57_RS08645 (AAAF57_08685) - 1881998..1882669 (+) 672 WP_155214076.1 potassium channel family protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58085.46 Da        Isoelectric Point: 5.1853

>NTDB_id=972984 AAAF57_RS08620 WP_014633896.1 1876606..1878135(-) (covS) [Streptococcus salivarius strain KSS5]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVIFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=972984 AAAF57_RS08620 WP_014633896.1 1876606..1878135(-) (covS) [Streptococcus salivarius strain KSS5]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTATTTTCTCAGCCAATACGCTACTTTTACAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATAGAAAAGGACTGGGACTCCGACGAAGAGTTGAGTCCAGAACCGCTTTTA
GCTGCCCTTTATTCGCCTAAAAATATCTATGCATCGATCATTAATGGCGTGCTTTCCGAAAAGCACTCTTTGGATGGTCA
GGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGATTCGCCTCCAGGTATGTCCGAGGTAAACAAATTGAAGTCAGTTTCCTATAAAGGGAAGCGTGGTTTC
TTGCTGCAAGTTCCAATCTACGGTAAGGATAAAAAGACCATCGTTGGTTATGCCCAAATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAC
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGCATGATGGATAAAAT
TCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTACGTACGCCGATTGCAGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAAGAAAGTCTTGAGGCTGCCAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAATTTCCGTGTCTTGCATGAAGACTACCAATTCTATCTCA
ATGATTTCGAGAGCTCAGAGCGCCCTGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTGCAAGTGCA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTATCGTTCAGATAAGGCACGTAACC
GTACGACAACGCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.804

100

0.998

Multiple sequence alignment