Detailed information NTG0972648

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC64_RS02345
• Genome accession: NZ_CP150788
• Coordinates: 511456..512343 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM20816
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 506456..517343

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC64_RS02315 (WOC64_02325)	-	507188..507949 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
WOC64_RS02320 (WOC64_02330)	-	508194..508649 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC64_RS02325 (WOC64_02335)	-	508771..508872 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC64_RS02330 (WOC64_02340)	-	508932..510356 (-)	1425	WP_000953744.1	alkaline phosphatase	-
WOC64_RS02335 (WOC64_02345)	-	510554..510754 (+)	201	WP_000604732.1	hypothetical protein	-
WOC64_RS02340 (WOC64_02350)	braR	510780..511445 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC64_RS02345 (WOC64_02355)	braS	511456..512343 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC64_RS02350 (WOC64_02360)	-	512451..513206 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC64_RS02355 (WOC64_02365)	-	513203..515203 (+)	2001	WP_000776751.1	ABC transporter permease	-
WOC64_RS02360 (WOC64_02370)	-	515862..515975 (+)	114	WP_011447078.1	hypothetical protein	-
WOC64_RS02365 (WOC64_02375)	-	516357..516617 (+)	261	WP_001789910.1	hypothetical protein	-
WOC64_RS02370 (WOC64_02380)	-	516627..517124 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC64_RS02375 (WOC64_02385)	-	517232..517324 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=972648 WOC64_RS02345 WP_000143419.1 511456..512343(+) (braS) [Staphylococcus aureus strain TUM20816]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=972648 WOC64_RS02345 WP_000143419.1 511456..512343(+) (braS) [Staphylococcus aureus strain TUM20816]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997