Detailed information NTG0972629

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC42_RS08615
• Genome accession: NZ_CP150786
• Coordinates: 1786885..1787772 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM20817
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1781885..1792772

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC42_RS08585 (WOC42_08585)	-	1782617..1783378 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
WOC42_RS08590 (WOC42_08590)	-	1783623..1784078 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC42_RS08595 (WOC42_08595)	-	1784200..1784301 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC42_RS08600 (WOC42_08600)	-	1784361..1785785 (-)	1425	WP_000953744.1	alkaline phosphatase	-
WOC42_RS08605 (WOC42_08605)	-	1785983..1786183 (+)	201	WP_000604728.1	hypothetical protein	-
WOC42_RS08610 (WOC42_08610)	braR	1786209..1786874 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC42_RS08615 (WOC42_08615)	braS	1786885..1787772 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC42_RS08620 (WOC42_08620)	-	1787880..1788635 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC42_RS08625 (WOC42_08625)	-	1788632..1790632 (+)	2001	WP_000776751.1	ABC transporter permease	-
WOC42_RS08630 (WOC42_08630)	-	1791291..1791404 (+)	114	WP_011447078.1	hypothetical protein	-
WOC42_RS08635 (WOC42_08635)	-	1791786..1792046 (+)	261	WP_001789910.1	hypothetical protein	-
WOC42_RS08640 (WOC42_08640)	-	1792056..1792553 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC42_RS08645 (WOC42_08645)	-	1792661..1792753 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=972629 WOC42_RS08615 WP_000143419.1 1786885..1787772(+) (braS) [Staphylococcus aureus strain TUM20817]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=972629 WOC42_RS08615 WP_000143419.1 1786885..1787772(+) (braS) [Staphylococcus aureus strain TUM20817]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997