Detailed information NTG0972569

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC49_RS07355
• Genome accession: NZ_CP150783
• Coordinates: 1464205..1465248 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM20818
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1459205..1470248

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC49_RS07325 (WOC49_07335)	-	1459576..1459686 (+)	111	WP_001790257.1	hypothetical protein	-
WOC49_RS07330 (WOC49_07340)	-	1459715..1460128 (+)	414	WP_001549145.1	hypothetical protein	-
WOC49_RS07335 (WOC49_07345)	-	1460559..1461545 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
WOC49_RS07340 (WOC49_07350)	map	1462131..1462889 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC49_RS07345 (WOC49_07355)	-	1463106..1463492 (+)	387	WP_001110179.1	hypothetical protein	-
WOC49_RS07350 (WOC49_07360)	liaF	1463507..1464208 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC49_RS07355 (WOC49_07365)	vraS	1464205..1465248 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC49_RS07360 (WOC49_07370)	vraR	1465238..1465867 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
WOC49_RS07365 (WOC49_07375)	-	1465983..1467200 (-)	1218	WP_000037069.1	YihY/virulence factor BrkB family protein	-
WOC49_RS07370 (WOC49_07380)	-	1467478..1467753 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC49_RS07375 (WOC49_07385)	-	1467760..1468224 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC49_RS07380 (WOC49_07390)	-	1468371..1468571 (+)	201	WP_000180461.1	DUF1128 family protein	-
WOC49_RS07385 (WOC49_07395)	-	1468574..1469830 (+)	1257	WP_108932452.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=972569 WOC49_RS07355 WP_001017131.1 1464205..1465248(+) (vraS) [Staphylococcus aureus strain TUM20818]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=972569 WOC49_RS07355 WP_001017131.1 1464205..1465248(+) (vraS) [Staphylococcus aureus strain TUM20818]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1