Detailed information NTG0972563

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC49_RS03285
• Genome accession: NZ_CP150783
• Coordinates: 692490..693377 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM20818
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 687490..698377

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC49_RS03255 (WOC49_03265)	-	688222..688983 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
WOC49_RS03260 (WOC49_03270)	-	689228..689683 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC49_RS03265 (WOC49_03275)	-	689805..689906 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC49_RS03270 (WOC49_03280)	-	689966..691390 (-)	1425	WP_000953744.1	alkaline phosphatase	-
WOC49_RS03275 (WOC49_03285)	-	691588..691788 (+)	201	WP_000604728.1	hypothetical protein	-
WOC49_RS03280 (WOC49_03290)	braR	691814..692479 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC49_RS03285 (WOC49_03295)	braS	692490..693377 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC49_RS03290 (WOC49_03300)	-	693485..694240 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC49_RS03295 (WOC49_03305)	-	694237..696237 (+)	2001	WP_000776751.1	ABC transporter permease	-
WOC49_RS03300 (WOC49_03310)	-	696896..697009 (+)	114	WP_011447078.1	hypothetical protein	-
WOC49_RS03305 (WOC49_03315)	-	697391..697651 (+)	261	WP_001789910.1	hypothetical protein	-
WOC49_RS03310 (WOC49_03320)	-	697661..698158 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC49_RS03315 (WOC49_03325)	-	698266..698358 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=972563 WOC49_RS03285 WP_000143419.1 692490..693377(+) (braS) [Staphylococcus aureus strain TUM20818]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=972563 WOC49_RS03285 WP_000143419.1 692490..693377(+) (braS) [Staphylococcus aureus strain TUM20818]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997