Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   WOC49_RS02615 Genome accession   NZ_CP150783
Coordinates   542841..544469 (+) Length   542 a.a.
NCBI ID   WP_108932401.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TUM20818     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 534619..551242 542841..544469 within 0


Gene organization within MGE regions


Location: 534619..551242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC49_RS02580 (WOC49_02590) - 534619..535116 (-) 498 WP_000051479.1 hypothetical protein -
  WOC49_RS02585 (WOC49_02595) - 535585..535962 (-) 378 WP_000687965.1 hypothetical protein -
  WOC49_RS02590 (WOC49_02600) - 536388..537320 (-) 933 WP_000364405.1 hypothetical protein -
  WOC49_RS02595 (WOC49_02605) - 537392..538975 (-) 1584 Protein_497 hypothetical protein -
  WOC49_RS02600 (WOC49_02610) ssb 539147..539443 (+) 297 WP_000221967.1 cassette chromosome ssDNA-binding protein -
  WOC49_RS02605 (WOC49_02615) cch1 539443..541236 (+) 1794 WP_108932402.1 cassette chromosome replicative helicase -
  WOC49_RS02610 (WOC49_02620) ccrA 541470..542819 (+) 1350 WP_000815640.1 cassette chromosome recombinase CcrA Machinery gene
  WOC49_RS02615 (WOC49_02625) ccrB 542841..544469 (+) 1629 WP_108932401.1 cassette chromosome recombinase CcrB Machinery gene
  WOC49_RS02620 (WOC49_02630) - 544991..545341 (+) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  WOC49_RS02625 (WOC49_02635) - 545428..545739 (+) 312 WP_000700851.1 DUF960 family protein -
  WOC49_RS02630 (WOC49_02640) - 545754..546260 (+) 507 WP_001092189.1 DUF1643 domain-containing protein -
  WOC49_RS02635 (WOC49_02645) - 546312..547908 (+) 1597 Protein_505 IS1182 family transposase -
  WOC49_RS02640 (WOC49_02650) - 547918..548160 (-) 243 Protein_506 type I restriction enzyme endonuclease domain-containing protein -
  WOC49_RS02645 (WOC49_02655) - 548150..549136 (-) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  WOC49_RS02650 (WOC49_02660) mecA 549233..551242 (+) 2010 WP_341263891.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62654.83 Da        Isoelectric Point: 9.7970

>NTDB_id=972559 WOC49_RS02615 WP_108932401.1 542841..544469(+) (ccrB) [Staphylococcus aureus strain TUM20818]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=972559 WOC49_RS02615 WP_108932401.1 542841..544469(+) (ccrB) [Staphylococcus aureus strain TUM20818]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCGACTGTGTTATG
GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTGCTATGCCAAAGGACATGGCTATCGTAAAATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAA
AGGGGAAACCTTTCAGTATTAGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAGAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACTCTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(11-156)

Recombinase (Recombinase)

(180-280)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

99.077

100

0.991

Multiple sequence alignment