Detailed information NTG0972521

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC53_RS04590
• Genome accession: NZ_CP150781
• Coordinates: 969925..970812 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM20820
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 964925..975812

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC53_RS04560 (WOC53_04550)	-	965657..966418 (+)	762	Protein_887	alpha/beta hydrolase	-
WOC53_RS04565 (WOC53_04555)	-	966663..967118 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC53_RS04570 (WOC53_04560)	-	967240..967341 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC53_RS04575 (WOC53_04565)	-	967401..968825 (-)	1425	WP_000953748.1	alkaline phosphatase	-
WOC53_RS04580 (WOC53_04570)	-	969023..969223 (+)	201	WP_000604727.1	hypothetical protein	-
WOC53_RS04585 (WOC53_04575)	braR	969249..969914 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC53_RS04590 (WOC53_04580)	braS	969925..970812 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC53_RS04595 (WOC53_04585)	-	970920..971675 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC53_RS04600 (WOC53_04590)	-	971672..973672 (+)	2001	WP_000776740.1	ABC transporter permease	-
WOC53_RS04605 (WOC53_04595)	-	974331..974444 (+)	114	Protein_896	hypothetical protein	-
WOC53_RS04610 (WOC53_04600)	-	974826..975086 (+)	261	WP_001791974.1	hypothetical protein	-
WOC53_RS04615 (WOC53_04605)	-	975096..975593 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC53_RS04620 (WOC53_04610)	-	975701..975793 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=972521 WOC53_RS04590 WP_000143417.1 969925..970812(+) (braS) [Staphylococcus aureus strain TUM20820]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=972521 WOC53_RS04590 WP_000143417.1 969925..970812(+) (braS) [Staphylococcus aureus strain TUM20820]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99