Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   WOC56_RS04140 Genome accession   NZ_CP150779
Coordinates   813386..814735 (-) Length   449 a.a.
NCBI ID   WP_000815640.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TUM20823     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 804970..821586 813386..814735 within 0


Gene organization within MGE regions


Location: 804970..821586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC56_RS04100 (WOC56_04105) mecA 804970..806979 (-) 2010 WP_341263891.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  WOC56_RS04105 (WOC56_04110) - 807076..808062 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  WOC56_RS04110 (WOC56_04115) - 808052..808294 (+) 243 Protein_805 type I restriction enzyme endonuclease domain-containing protein -
  WOC56_RS04115 (WOC56_04120) - 808285..809896 (-) 1612 Protein_806 IS1182 family transposase -
  WOC56_RS04120 (WOC56_04125) - 809945..810451 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  WOC56_RS04125 (WOC56_04130) - 810466..810777 (-) 312 WP_000700851.1 DUF960 family protein -
  WOC56_RS04130 (WOC56_04135) - 810864..811214 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  WOC56_RS04135 (WOC56_04140) ccrB 811736..813364 (-) 1629 WP_108932401.1 cassette chromosome recombinase CcrB Machinery gene
  WOC56_RS04140 (WOC56_04145) ccrA 813386..814735 (-) 1350 WP_000815640.1 cassette chromosome recombinase CcrA Machinery gene
  WOC56_RS04145 (WOC56_04150) cch1 814969..816762 (-) 1794 WP_108932402.1 cassette chromosome replicative helicase -
  WOC56_RS04150 (WOC56_04155) ssb 816762..817058 (-) 297 WP_000221967.1 cassette chromosome ssDNA-binding protein -
  WOC56_RS04155 (WOC56_04160) - 817230..818813 (+) 1584 Protein_814 hypothetical protein -
  WOC56_RS04160 (WOC56_04165) - 818885..819817 (+) 933 WP_000364405.1 hypothetical protein -
  WOC56_RS04165 (WOC56_04170) - 820243..820620 (+) 378 WP_000687965.1 hypothetical protein -
  WOC56_RS04170 (WOC56_04175) - 821089..821586 (+) 498 WP_000051479.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52663.34 Da        Isoelectric Point: 9.9639

>NTDB_id=972476 WOC56_RS04140 WP_000815640.1 813386..814735(-) (ccrA) [Staphylococcus aureus strain TUM20823]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHIIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=972476 WOC56_RS04140 WP_000815640.1 813386..814735(-) (ccrA) [Staphylococcus aureus strain TUM20823]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGTCGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAGTGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAGCAAACACAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACATCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATTGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Recombinase (Recombinase)

(169-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

97.55

100

0.976
  ccrA Staphylococcus aureus COL

75.947

100

0.759

Multiple sequence alignment