Detailed information NTG0972453

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC48_RS09135
• Genome accession: NZ_CP150777
• Coordinates: 1873356..1874243 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM20825
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1868356..1879243

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC48_RS09105 (WOC48_09075)	-	1869088..1869849 (+)	762	Protein_1791	alpha/beta hydrolase	-
WOC48_RS09110 (WOC48_09080)	-	1870094..1870549 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC48_RS09115 (WOC48_09085)	-	1870671..1870772 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC48_RS09120 (WOC48_09090)	-	1870832..1872256 (-)	1425	WP_000953748.1	alkaline phosphatase	-
WOC48_RS09125 (WOC48_09095)	-	1872454..1872654 (+)	201	WP_000604727.1	hypothetical protein	-
WOC48_RS09130 (WOC48_09100)	braR	1872680..1873345 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC48_RS09135 (WOC48_09105)	braS	1873356..1874243 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC48_RS09140 (WOC48_09110)	-	1874351..1875106 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC48_RS09145 (WOC48_09115)	-	1875103..1877103 (+)	2001	WP_000776740.1	ABC transporter permease	-
WOC48_RS09150 (WOC48_09120)	-	1877762..1877875 (+)	114	Protein_1800	hypothetical protein	-
WOC48_RS09155 (WOC48_09125)	-	1878257..1878517 (+)	261	WP_001791974.1	hypothetical protein	-
WOC48_RS09160 (WOC48_09130)	-	1878527..1879024 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC48_RS09165 (WOC48_09135)	-	1879132..1879224 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=972453 WOC48_RS09135 WP_000143417.1 1873356..1874243(+) (braS) [Staphylococcus aureus strain TUM20825]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=972453 WOC48_RS09135 WP_000143417.1 1873356..1874243(+) (braS) [Staphylococcus aureus strain TUM20825]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99