Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   WOC57_RS10185 Genome accession   NZ_CP150775
Coordinates   2064867..2065583 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain TUM20888     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2059867..2070583
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC57_RS10165 (WOC57_10180) - 2060961..2061911 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  WOC57_RS10170 (WOC57_10185) - 2062060..2063544 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  WOC57_RS10175 (WOC57_10190) - 2063541..2064500 (+) 960 WP_001253312.1 carbohydrate kinase -
  WOC57_RS10180 (WOC57_10195) - 2064688..2064795 (-) 108 WP_001790167.1 hypothetical protein -
  WOC57_RS10185 (WOC57_10200) agrA 2064867..2065583 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  WOC57_RS10190 (WOC57_10205) agrC 2065602..2066894 (-) 1293 WP_368409944.1 quorum-sensing sensor histidine kinase AgrC -
  WOC57_RS10195 (WOC57_10210) agrD 2066919..2067059 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  WOC57_RS10200 (WOC57_10215) agrB 2067056..2067625 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  WOC57_RS10205 (WOC57_10220) hld 2067915..2067995 (+) 81 WP_000046022.1 delta-hemolysin -
  WOC57_RS10210 (WOC57_10225) - 2068592..2069377 (-) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  WOC57_RS10215 (WOC57_10230) - 2069738..2070364 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=972399 WOC57_RS10185 WP_000688492.1 2064867..2065583(-) (agrA) [Staphylococcus aureus strain TUM20888]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=972399 WOC57_RS10185 WP_000688492.1 2064867..2065583(-) (agrA) [Staphylococcus aureus strain TUM20888]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment