Detailed information NTG0972364

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC62_RS08915
• Genome accession: NZ_CP150773
• Coordinates: 1829321..1830208 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM20913
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1824321..1835208

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC62_RS08885 (WOC62_08870)	-	1825053..1825814 (+)	762	Protein_1748	alpha/beta hydrolase	-
WOC62_RS08890 (WOC62_08875)	-	1826059..1826514 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC62_RS08895 (WOC62_08880)	-	1826636..1826737 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC62_RS08900 (WOC62_08885)	-	1826797..1828221 (-)	1425	WP_000953748.1	alkaline phosphatase	-
WOC62_RS08905 (WOC62_08890)	-	1828419..1828619 (+)	201	WP_000604727.1	hypothetical protein	-
WOC62_RS08910 (WOC62_08895)	braR	1828645..1829310 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC62_RS08915 (WOC62_08900)	braS	1829321..1830208 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC62_RS08920 (WOC62_08905)	-	1830316..1831071 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC62_RS08925 (WOC62_08910)	-	1831068..1833068 (+)	2001	WP_000776740.1	ABC transporter permease	-
WOC62_RS08930 (WOC62_08915)	-	1833727..1833840 (+)	114	Protein_1757	hypothetical protein	-
WOC62_RS08935 (WOC62_08920)	-	1834222..1834482 (+)	261	WP_001791974.1	hypothetical protein	-
WOC62_RS08940 (WOC62_08925)	-	1834492..1834989 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC62_RS08945 (WOC62_08930)	-	1835097..1835189 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=972364 WOC62_RS08915 WP_000143417.1 1829321..1830208(+) (braS) [Staphylococcus aureus strain TUM20913]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=972364 WOC62_RS08915 WP_000143417.1 1829321..1830208(+) (braS) [Staphylococcus aureus strain TUM20913]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99