Detailed information NTG0972333

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC60_RS13880
• Genome accession: NZ_CP150771
• Coordinates: 2774390..2775277 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM20914
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2769390..2780277

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC60_RS13850 (WOC60_13865)	-	2769409..2769501 (+)	93	WP_010956583.1	hypothetical protein	-
WOC60_RS13855 (WOC60_13870)	-	2769609..2770106 (-)	498	WP_001065268.1	glutathione peroxidase	-
WOC60_RS13860 (WOC60_13875)	-	2770116..2770376 (-)	261	WP_001789910.1	hypothetical protein	-
WOC60_RS13865 (WOC60_13880)	-	2770758..2770871 (-)	114	WP_011447078.1	hypothetical protein	-
WOC60_RS13870 (WOC60_13885)	-	2771530..2773530 (-)	2001	WP_000776751.1	ABC transporter permease	-
WOC60_RS13875 (WOC60_13890)	-	2773527..2774282 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC60_RS13880 (WOC60_13895)	braS	2774390..2775277 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC60_RS13885 (WOC60_13900)	braR	2775288..2775953 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC60_RS13890 (WOC60_13905)	-	2775979..2776179 (-)	201	WP_000604728.1	hypothetical protein	-
WOC60_RS13895 (WOC60_13910)	-	2776377..2777801 (+)	1425	WP_000953744.1	alkaline phosphatase	-
WOC60_RS13900	-	2777861..2777962 (-)	102	WP_000731972.1	SE2200 family small protein	-
WOC60_RS13905 (WOC60_13920)	-	2778084..2778539 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC60_RS13910 (WOC60_13925)	-	2778784..2779545 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=972333 WOC60_RS13880 WP_000143419.1 2774390..2775277(-) (braS) [Staphylococcus aureus strain TUM20914]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=972333 WOC60_RS13880 WP_000143419.1 2774390..2775277(-) (braS) [Staphylococcus aureus strain TUM20914]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997