Detailed information NTG0972285

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC59_RS12420
• Genome accession: NZ_CP150769
• Coordinates: 2436740..2437627 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM20915
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2431740..2442627

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC59_RS12390 (WOC59_12370)	-	2431759..2431851 (+)	93	WP_010956583.1	hypothetical protein	-
WOC59_RS12395 (WOC59_12375)	-	2431959..2432456 (-)	498	WP_001065268.1	glutathione peroxidase	-
WOC59_RS12400 (WOC59_12380)	-	2432466..2432726 (-)	261	WP_001791974.1	hypothetical protein	-
WOC59_RS12405 (WOC59_12385)	-	2433108..2433221 (-)	114	Protein_2400	hypothetical protein	-
WOC59_RS12410 (WOC59_12390)	-	2433880..2435880 (-)	2001	WP_000776740.1	ABC transporter permease	-
WOC59_RS12415 (WOC59_12395)	-	2435877..2436632 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC59_RS12420 (WOC59_12400)	braS	2436740..2437627 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC59_RS12425 (WOC59_12405)	braR	2437638..2438303 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC59_RS12430 (WOC59_12410)	-	2438329..2438529 (-)	201	WP_000604727.1	hypothetical protein	-
WOC59_RS12435 (WOC59_12415)	-	2438727..2440151 (+)	1425	WP_000953748.1	alkaline phosphatase	-
WOC59_RS12440	-	2440211..2440312 (-)	102	WP_000731972.1	SE2200 family small protein	-
WOC59_RS12445 (WOC59_12425)	-	2440434..2440889 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC59_RS12450 (WOC59_12430)	-	2441134..2441895 (-)	762	Protein_2409	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=972285 WOC59_RS12420 WP_000143417.1 2436740..2437627(-) (braS) [Staphylococcus aureus strain TUM20915]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=972285 WOC59_RS12420 WP_000143417.1 2436740..2437627(-) (braS) [Staphylococcus aureus strain TUM20915]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99