Detailed information NTG0972279

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC59_RS08600
• Genome accession: NZ_CP150769
• Coordinates: 1705247..1706290 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM20915
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1700247..1711290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC59_RS08570 (WOC59_08550)	-	1700675..1701931 (-)	1257	WP_001793428.1	aminopeptidase	-
WOC59_RS08575 (WOC59_08555)	-	1701934..1702134 (-)	201	WP_000180460.1	DUF1128 family protein	-
WOC59_RS08580 (WOC59_08560)	-	1702281..1702745 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC59_RS08585 (WOC59_08565)	-	1702752..1703027 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC59_RS08590 (WOC59_08570)	-	1703305..1704516 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
WOC59_RS08595 (WOC59_08575)	vraR	1704628..1705257 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
WOC59_RS08600 (WOC59_08580)	vraS	1705247..1706290 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC59_RS08605 (WOC59_08585)	liaF	1706287..1706988 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC59_RS08610 (WOC59_08590)	-	1707003..1707389 (-)	387	WP_001110179.1	hypothetical protein	-
WOC59_RS08615 (WOC59_08595)	map	1707606..1708364 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC59_RS08620 (WOC59_08600)	-	1708895..1709881 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
WOC59_RS08625 (WOC59_08605)	-	1710371..1710784 (-)	414	WP_001837236.1	hypothetical protein	-
WOC59_RS08630 (WOC59_08610)	-	1710813..1710924 (-)	112	Protein_1659	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=972279 WOC59_RS08600 WP_001017131.1 1705247..1706290(-) (vraS) [Staphylococcus aureus strain TUM20915]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=972279 WOC59_RS08600 WP_001017131.1 1705247..1706290(-) (vraS) [Staphylococcus aureus strain TUM20915]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1