Detailed information NTG0972225

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC51_RS03740
• Genome accession: NZ_CP150767
• Coordinates: 769573..770616 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM20926
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 764573..775616

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC51_RS03710 (WOC51_03695)	-	765001..766257 (-)	1257	WP_001793428.1	aminopeptidase	-
WOC51_RS03715 (WOC51_03700)	-	766260..766460 (-)	201	WP_000180460.1	DUF1128 family protein	-
WOC51_RS03720 (WOC51_03705)	-	766607..767071 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC51_RS03725 (WOC51_03710)	-	767078..767353 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC51_RS03730 (WOC51_03715)	-	767631..768842 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
WOC51_RS03735 (WOC51_03720)	vraR	768954..769583 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
WOC51_RS03740 (WOC51_03725)	vraS	769573..770616 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC51_RS03745 (WOC51_03730)	liaF	770613..771314 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC51_RS03750 (WOC51_03735)	-	771329..771715 (-)	387	WP_001110179.1	hypothetical protein	-
WOC51_RS03755 (WOC51_03740)	map	771932..772690 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC51_RS03760 (WOC51_03745)	-	773221..774207 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
WOC51_RS03765 (WOC51_03750)	-	774756..775169 (-)	414	WP_001837236.1	hypothetical protein	-
WOC51_RS03770 (WOC51_03755)	-	775198..775309 (-)	112	Protein_714	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=972225 WOC51_RS03740 WP_001017131.1 769573..770616(-) (vraS) [Staphylococcus aureus strain TUM20926]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=972225 WOC51_RS03740 WP_001017131.1 769573..770616(-) (vraS) [Staphylococcus aureus strain TUM20926]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1