Detailed information NTG0972201

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC50_RS11115
• Genome accession: NZ_CP150766
• Coordinates: 2254625..2255512 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM20929
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2249625..2260512

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC50_RS11085 (WOC50_11095)	-	2250357..2251118 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
WOC50_RS11090 (WOC50_11100)	-	2251363..2251818 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC50_RS11095 (WOC50_11105)	-	2251940..2252041 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC50_RS11100 (WOC50_11110)	-	2252101..2253525 (-)	1425	WP_000953744.1	alkaline phosphatase	-
WOC50_RS11105 (WOC50_11115)	-	2253723..2253923 (+)	201	WP_000604732.1	hypothetical protein	-
WOC50_RS11110 (WOC50_11120)	braR	2253949..2254614 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC50_RS11115 (WOC50_11125)	braS	2254625..2255512 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC50_RS11120 (WOC50_11130)	-	2255620..2256375 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC50_RS11125 (WOC50_11135)	-	2256372..2258372 (+)	2001	WP_000776751.1	ABC transporter permease	-
WOC50_RS11130 (WOC50_11140)	-	2259031..2259144 (+)	114	WP_011447078.1	hypothetical protein	-
WOC50_RS11135 (WOC50_11145)	-	2259526..2259786 (+)	261	WP_001789910.1	hypothetical protein	-
WOC50_RS11140 (WOC50_11150)	-	2259796..2260293 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC50_RS11145 (WOC50_11155)	-	2260401..2260493 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=972201 WOC50_RS11115 WP_000143419.1 2254625..2255512(+) (braS) [Staphylococcus aureus strain TUM20929]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=972201 WOC50_RS11115 WP_000143419.1 2254625..2255512(+) (braS) [Staphylococcus aureus strain TUM20929]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997