Detailed information NTG0972164

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC50_RS01185
• Genome accession: NZ_CP150766
• Coordinates: 206936..207979 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM20929
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 201936..212979

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC50_RS01155 (WOC50_01155)	-	202247..202357 (+)	111	WP_001790257.1	hypothetical protein	-
WOC50_RS01160 (WOC50_01160)	-	202386..202799 (+)	414	WP_001549145.1	hypothetical protein	-
WOC50_RS01165 (WOC50_01165)	-	203289..204275 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
WOC50_RS01170 (WOC50_01170)	map	204862..205620 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC50_RS01175 (WOC50_01175)	-	205837..206223 (+)	387	WP_001110179.1	hypothetical protein	-
WOC50_RS01180 (WOC50_01180)	liaF	206238..206939 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC50_RS01185 (WOC50_01185)	vraS	206936..207979 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC50_RS01190 (WOC50_01190)	vraR	207969..208598 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
WOC50_RS01195 (WOC50_01195)	-	208714..209931 (-)	1218	WP_000037069.1	YihY/virulence factor BrkB family protein	-
WOC50_RS01200 (WOC50_01200)	-	210209..210484 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC50_RS01205 (WOC50_01205)	-	210491..210955 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC50_RS01210 (WOC50_01210)	-	211102..211302 (+)	201	WP_000180461.1	DUF1128 family protein	-
WOC50_RS01215 (WOC50_01215)	-	211305..212561 (+)	1257	WP_001795438.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=972164 WOC50_RS01185 WP_001017131.1 206936..207979(+) (vraS) [Staphylococcus aureus strain TUM20929]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=972164 WOC50_RS01185 WP_001017131.1 206936..207979(+) (vraS) [Staphylococcus aureus strain TUM20929]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1