Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   WOC41_RS08250 Genome accession   NZ_CP150763
Coordinates   1662299..1662868 (+) Length   189 a.a.
NCBI ID   WP_000872877.1    Uniprot ID   A0A641A2F3
Organism   Staphylococcus aureus strain TUM20967     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1657299..1667868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC41_RS08225 (WOC41_08215) cysE 1658512..1659159 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  WOC41_RS08230 (WOC41_08220) cysS 1659143..1660543 (+) 1401 WP_000631973.1 cysteine--tRNA ligase -
  WOC41_RS08235 (WOC41_08225) - 1660536..1660940 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  WOC41_RS08240 (WOC41_08230) rlmB 1660948..1661694 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  WOC41_RS08245 (WOC41_08235) - 1661694..1662218 (+) 525 WP_000664738.1 NYN domain-containing protein -
  WOC41_RS08250 (WOC41_08240) sigH 1662299..1662868 (+) 570 WP_000872877.1 sigma-70 family RNA polymerase sigma factor Regulator
  WOC41_RS08255 (WOC41_08245) rpmG 1662983..1663126 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  WOC41_RS08260 (WOC41_08250) secE 1663182..1663364 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  WOC41_RS08265 (WOC41_08255) nusG 1663377..1663925 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  WOC41_RS08270 (WOC41_08260) rplK 1664106..1664528 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  WOC41_RS08275 (WOC41_08265) rplA 1664736..1665428 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  WOC41_RS08280 (WOC41_08270) rplJ 1665700..1666200 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  WOC41_RS08285 (WOC41_08275) rplL 1666243..1666611 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  WOC41_RS08290 (WOC41_08280) - 1666786..1667394 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=972094 WOC41_RS08250 WP_000872877.1 1662299..1662868(+) (sigH) [Staphylococcus aureus strain TUM20967]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSVFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=972094 WOC41_RS08250 WP_000872877.1 1662299..1662868(+) (sigH) [Staphylococcus aureus strain TUM20967]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGTATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641A2F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

100

100

1
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment