Detailed information NTG0972080

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC41_RS01390
• Genome accession: NZ_CP150763
• Coordinates: 266190..267233 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM20967
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 261190..272233

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC41_RS01360 (WOC41_01355)	-	261618..262874 (-)	1257	WP_001793428.1	aminopeptidase	-
WOC41_RS01365 (WOC41_01360)	-	262877..263077 (-)	201	WP_000180460.1	DUF1128 family protein	-
WOC41_RS01370 (WOC41_01365)	-	263224..263688 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC41_RS01375 (WOC41_01370)	-	263695..263970 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC41_RS01380 (WOC41_01375)	-	264248..265459 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
WOC41_RS01385 (WOC41_01380)	vraR	265571..266200 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
WOC41_RS01390 (WOC41_01385)	vraS	266190..267233 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC41_RS01395 (WOC41_01390)	liaF	267230..267931 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC41_RS01400 (WOC41_01395)	-	267946..268332 (-)	387	WP_001110179.1	hypothetical protein	-
WOC41_RS01405 (WOC41_01400)	map	268549..269307 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC41_RS01410 (WOC41_01405)	-	269838..270824 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
WOC41_RS01415 (WOC41_01410)	-	271315..271728 (-)	414	WP_001837236.1	hypothetical protein	-
WOC41_RS01420 (WOC41_01415)	-	271757..271868 (-)	112	Protein_246	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=972080 WOC41_RS01390 WP_001017131.1 266190..267233(-) (vraS) [Staphylococcus aureus strain TUM20967]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=972080 WOC41_RS01390 WP_001017131.1 266190..267233(-) (vraS) [Staphylococcus aureus strain TUM20967]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1