Detailed information NTG0972055

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC47_RS06865
• Genome accession: NZ_CP150761
• Coordinates: 1279690..1280577 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM22173
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1274690..1285577

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC47_RS06835 (WOC47_06835)	-	1274709..1274801 (+)	93	WP_010956583.1	hypothetical protein	-
WOC47_RS06840 (WOC47_06840)	-	1274909..1275406 (-)	498	WP_001065268.1	glutathione peroxidase	-
WOC47_RS06845 (WOC47_06845)	-	1275416..1275676 (-)	261	WP_001789910.1	hypothetical protein	-
WOC47_RS06850 (WOC47_06850)	-	1276058..1276171 (-)	114	WP_001791776.1	hypothetical protein	-
WOC47_RS06855 (WOC47_06855)	-	1276830..1278830 (-)	2001	WP_000776751.1	ABC transporter permease	-
WOC47_RS06860 (WOC47_06860)	-	1278827..1279582 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC47_RS06865 (WOC47_06865)	braS	1279690..1280577 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC47_RS06870 (WOC47_06870)	braR	1280588..1281253 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC47_RS06875 (WOC47_06875)	-	1281279..1281479 (-)	201	WP_000604728.1	hypothetical protein	-
WOC47_RS06880 (WOC47_06880)	-	1281677..1283101 (+)	1425	WP_000953744.1	alkaline phosphatase	-
WOC47_RS06885	-	1283161..1283262 (-)	102	WP_000731972.1	SE2200 family small protein	-
WOC47_RS06890 (WOC47_06890)	-	1283384..1283839 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC47_RS06895 (WOC47_06895)	-	1284084..1284845 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=972055 WOC47_RS06865 WP_000143419.1 1279690..1280577(-) (braS) [Staphylococcus aureus strain TUM22173]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=972055 WOC47_RS06865 WP_000143419.1 1279690..1280577(-) (braS) [Staphylococcus aureus strain TUM22173]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997