Detailed information NTG0972050

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC47_RS02945
• Genome accession: NZ_CP150761
• Coordinates: 537497..538540 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM22173
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 532497..543540

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC47_RS02915 (WOC47_02915)	-	532915..534171 (-)	1257	WP_001795438.1	aminopeptidase	-
WOC47_RS02920 (WOC47_02920)	-	534174..534374 (-)	201	WP_000180461.1	DUF1128 family protein	-
WOC47_RS02925 (WOC47_02925)	-	534521..534985 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC47_RS02930 (WOC47_02930)	-	534992..535267 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC47_RS02935 (WOC47_02935)	-	535545..536762 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
WOC47_RS02940 (WOC47_02940)	vraR	536878..537507 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
WOC47_RS02945 (WOC47_02945)	vraS	537497..538540 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC47_RS02950 (WOC47_02950)	liaF	538537..539238 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC47_RS02955 (WOC47_02955)	-	539253..539639 (-)	387	WP_001110179.1	hypothetical protein	-
WOC47_RS02960 (WOC47_02960)	map	539856..540614 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC47_RS02965 (WOC47_02965)	-	541142..542128 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
WOC47_RS02970 (WOC47_02970)	-	542559..542972 (-)	414	WP_001549145.1	hypothetical protein	-
WOC47_RS02975 (WOC47_02975)	-	543001..543111 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=972050 WOC47_RS02945 WP_001017131.1 537497..538540(-) (vraS) [Staphylococcus aureus strain TUM22173]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=972050 WOC47_RS02945 WP_001017131.1 537497..538540(-) (vraS) [Staphylococcus aureus strain TUM22173]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1